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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The complex cartography of stem cell commitment.

In this issue of Cell, a study by Adolfsson and coworkers (Adolfsson et al., 2005) provides insight into the early lineage commitment events of multipotent hematopoietic stem cells (HSCs). These studies demonstrate the importance of the Flt3 receptor tyrosine kinase as the earliest marker of hematopoietic cell fate commitment in that erythrocyte and megakaryocyte potentials are lost first as HSCs differentiate to lymphocyte progenitors.[1]

References

  1. The complex cartography of stem cell commitment. Akashi, K., Traver, D., Zon, L.I. Cell (2005) [Pubmed]
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