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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Giant congenital melanocytic naevus in association with hepatic melanin deposits.

This report describes a neonate with a giant congenital pigmented naevus over most of the trunk surface area, along with multiple satellite lesions, especially over the legs. Magnetic resonance imaging of the abdomen showed large deposits of melanin in the glutei bilaterally, the rectus abdominis muscles and the liver. Treatment consisted of repeated dermabrasion of the naevus over the lower back with CO2 laser (Silk Touch), followed by autologous skin grafting. No evidence of malignant transformation was observed. Conclusion: Giant congenital melanocytic naevus may be associated with involvement of internal organs other than the central nervous system.[1]


  1. Giant congenital melanocytic naevus in association with hepatic melanin deposits. Prais, D., Nussinovitch, M., Kornreich, L., Amir, J. Acta Paediatr. (2005) [Pubmed]
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