Disease relevance of Dermabrasion

• Macular amyloid and lichen amyloidosus generally follow a chronic course with intractable pruritus; there have been isolated reports of the beneficial effect of dermabrasion, topical dimethylsulfoxide, and therapy with the aromatic retinoid, etretinate [1].
• Shave excision and dermabrasion of midline angiofibroma in tuberous sclerosis [2].
• Six areas of the face and forehead of a 36-year-old white female presenting with a benign congenital blue nevus of the skin were treated by dermabrasion, bichloracetic acid, and the classic phenol peel [3].

High impact information on Dermabrasion

• In the skin, we did not document a migration defect after full thickness wounds but did observe cell proliferation delays and reduced localization of alpha9 integrin in the syndecan-1(-/-) epidermis after dermabrasion [4].
• Using a (3)H(2)O penetration assay to evaluate barrier integrity, the amount of latex protein penetration was found to positively correlate with the degree of dermabrasion [5].
• METHODS: Focal chemical peeling, carbon dioxide (CO2) laser, scar excision, punch grafting, and dermabrasion were used [6].
• Pulsed carbon dioxide laser, trichloroacetic acid, Baker-Gordon phenol, and dermabrasion: a comparative clinical and histologic study of cutaneous resurfacing in a porcine model [7].
• Significant increases in type I pN-collagen, type III pN-collagen, and TGF-beta 1 occurred in the papillary dermis after both types of dermabrasion [8].

Biological context of Dermabrasion

• This study comparatively assessed the alteration in dermal histology and mechanical properties of skin following treatment with 25% and 50% trichloroacetic acid, Baker's phenol solution, and dermabrasion [9].
• Retinoic acid (RA) and glycolic acid (GA) are frequently used in the treatment of acne and skin aging, as well as improving skin healing after dermabrasion and in photoaged skin [10].

Anatomical context of Dermabrasion

• We report two cases of scleromyxedema treated with melphalan (alkeran) and dermabrasion, both patients with central nervous system involvement [11].
• They were clearly different from those seen on dermabrasion at this site in normal skin and in patients with vitiligo where the area is lighter red with only small punctual bleedings from arterial capillaries [12].

Associations of Dermabrasion with chemical compounds

• Tretinoin in the preoperative and postoperative management of dermabrasion [13].
• This is the first reported case of atypical scarring in a patient who began isotretinoin therapy 2 months after dermabrasion [14].
• Dermabrasion vs 5-FU for actinic damage [15].
• Discoid lupus erythematosus scarring and dermabrasion: a case report and discussion [16].
• Prophylaxis with oral acyclovir of "at risk" patients prior to dermabrasion is proposed [17].

Gene context of Dermabrasion

• Vitiligo: treatment by dermabrasion and epithelial sheet grafting [18].
• Dermabrasion and limited excision of the fibrous papules of tuberous sclerosis: case report [19].
• Treatment consisted of shave excision of long slightly vascular "shag-rug" papules, followed by repeated deep dermabrasion [2].
• The result seen with less skilled dermabraders was significantly worse than all other methods (p < 0.009).The free electron laser at 7.7 microm, which is preferentially absorbed by the proteins of the extracellular matrix, provided better scar reduction than the CO2 resurfacing laser and dermabrasion [20].
• Effect of topical tretinoin, chemical peeling and dermabrasion on p53 expression in facial skin [21].

Analytical, diagnostic and therapeutic context of Dermabrasion

• Pretreatment of nonischemic animals (n = 13) used for the dermabrasion bioassay with diethylcarbamazine abolished diapedesis into the plastic chambers induced by ischemic plasma (n = 5) (32 +/- 24 PMN/mm3) or LTB4 (n = 3) (36 +/- 28 PMN/mm3) [22].
• The existing therapies such as topical 5-fluorouracil, chemical peels, cryotherapy, dermabrasion, and CO2 laser resurfacing can produce prolonged recovery time or are often operator dependent [23].
• METHODS: Topical retinoic and glycolic acid preparations, chemical peels, botulinum and collagen injections, dermabrasion, and laser resurfacing procedures for periorbital skin rejuvenation were reviewed [24].
• Aluminum oxide crystal microdermabrasion, a newly developed technique, has the advantages of less bleeding, fewer complications, better compliance, and no need for local anesthesia or high surgical skill in comparison with traditional dermabrasion [25].
• Treatment consisted of repeated dermabrasion of the naevus over the lower back with CO2 laser (Silk Touch), followed by autologous skin grafting [26].

References