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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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SERT and DAT availabilities under citalopram treatment in obsessive-compulsive disorder (OCD).

Serotonin and dopamine transporter (SERT, DAT) availabilities have prospectively been investigated using [123I]beta-CIT and single photon emission computed tomography in subjects with obsessive-compulsive disorder under treatment with the selective serotonin reuptake inhibitor citalopram. SERT availability decreased by a mean 36.5%, whereas DAT availability increased by about 40%. The data point at a citalopram induced modulation of both serotonergic and dopaminergic activity and support the notion of functional interactions of monoaminergic systems in the human brain.[1]

References

  1. SERT and DAT availabilities under citalopram treatment in obsessive-compulsive disorder (OCD). Pogarell, O., Poepperl, G., Mulert, C., Hamann, C., Sadowsky, N., Riedel, M., Moeller, H.J., Hegerl, U., Tatsch, K. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2005) [Pubmed]
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