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MeSH Review

Tomography, Emission-Computed, Single-Photon

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Disease relevance of Tomography, Emission-Computed, Single-Photon


Psychiatry related information on Tomography, Emission-Computed, Single-Photon


High impact information on Tomography, Emission-Computed, Single-Photon


Chemical compound and disease context of Tomography, Emission-Computed, Single-Photon


Biological context of Tomography, Emission-Computed, Single-Photon


Anatomical context of Tomography, Emission-Computed, Single-Photon


Associations of Tomography, Emission-Computed, Single-Photon with chemical compounds


Gene context of Tomography, Emission-Computed, Single-Photon

  • Patients with ADHD and with a history of nicotine abuse both displayed lower values of DAT density in [99mTc]TRODAT-1 SPECT than non-smokers with ADHD [34].
  • CONCLUSION: Molecular imaging of the functional transport activity of MDR1 Pgp with ((67/68)Ga-[3-ethoxy-ENBDMPI])(+) may enable noninvasive SPECT/PET monitoring of the blood-brain barrier, chemotherapeutic regimens, and MDR1 gene therapy protocols in vivo [35].
  • We assessed striatal DA D2 receptor occupancy by olanzapine and risperidone in 36 young patients [31 males, 5 females; mean age 21.1 years (16-28)] with first episode schizophrenia, using [123I]iodobenzamide (IBZM) SPECT [36].
  • The rCBF was compared between ADHD patients with and without risk alleles at DRD4 (7-repeat allele) and/or at DAT1 (homozygosis for the 10-repeat allele) genes by single photon emission computed tomography (SPECT) during continuous performance test [37].
  • 99mTc-HMPAO Brain SPECT is useful in the diagnosing and assessment of the progress of MERRF, MELAS and KSS [38].

Analytical, diagnostic and therapeutic context of Tomography, Emission-Computed, Single-Photon


  1. Prediction of death and myocardial infarction by screening with exercise-thallium testing after coronary-artery-bypass grafting. Lauer, M.S., Lytle, B., Pashkow, F., Snader, C.E., Marwick, T.H. Lancet (1998) [Pubmed]
  2. Dopamine agonist monotherapy in Parkinson's disease. Clarke, C.E., Guttman, M. Lancet (2002) [Pubmed]
  3. Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. Dakik, H.A., Kleiman, N.S., Farmer, J.A., He, Z.X., Wendt, J.A., Pratt, C.M., Verani, M.S., Mahmarian, J.J. Circulation (1998) [Pubmed]
  4. Dual isotope thallium and indium antimyosin SPECT imaging to identify acute infarct patients at further ischemic risk. Johnson, L.L., Seldin, D.W., Keller, A.M., Wall, R.M., Bhatia, K., Bingham, C.O., Tresgallo, M.E. Circulation (1990) [Pubmed]
  5. Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose. Bonow, R.O., Dilsizian, V., Cuocolo, A., Bacharach, S.L. Circulation (1991) [Pubmed]
  6. In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease, and Parkinson's disease. Kuhl, D.E., Minoshima, S., Fessler, J.A., Frey, K.A., Foster, N.L., Ficaro, E.P., Wieland, D.M., Koeppe, R.A. Ann. Neurol. (1996) [Pubmed]
  7. Influence of motor activity on striatal dopamine release: A study using iodobenzamide and SPECT. Larisch, R., Schommartz, B., Vosberg, H., Müller-Gärtner, H.W. Neuroimage (1999) [Pubmed]
  8. Abnormal regional cerebral blood flow in childhood autism. Ohnishi, T., Matsuda, H., Hashimoto, T., Kunihiro, T., Nishikawa, M., Uema, T., Sasaki, M. Brain (2000) [Pubmed]
  9. [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder. Malison, R.T., McDougle, C.J., van Dyck, C.H., Scahill, L., Baldwin, R.M., Seibyl, J.P., Price, L.H., Leckman, J.F., Innis, R.B. The American journal of psychiatry. (1995) [Pubmed]
  10. Subjective experience and striatal dopamine D(2) receptor occupancy in patients with schizophrenia stabilized by olanzapine or risperidone. de Haan, L., Lavalaye, J., Linszen, D., Dingemans, P.M., Booij, J. The American journal of psychiatry. (2000) [Pubmed]
  11. Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. Tiihonen, J., Kuikka, J., Bergström, K., Hakola, P., Karhu, J., Ryynänen, O.P., Föhr, J. Nat. Med. (1995) [Pubmed]
  12. Localization of D-2 dopamine receptors to intrinsic striatal neurones by quantitative autoradiography. Trugman, J.M., Geary, W.A., Wooten, G.F. Nature (1986) [Pubmed]
  13. Independent influences of body mass and gastric volumes on satiation in humans. Delgado-Aros, S., Cremonini, F., Castillo, J.E., Chial, H.J., Burton, D.D., Ferber, I., Camilleri, M. Gastroenterology (2004) [Pubmed]
  14. Visualisation of cell death in vivo in patients with acute myocardial infarction. Hofstra, L., Liem, I.H., Dumont, E.A., Boersma, H.H., van Heerde, W.L., Doevendans, P.A., De Muinck, E., Wellens, H.J., Kemerink, G.J., Reutelingsperger, C.P., Heidendal, G.A. Lancet (2000) [Pubmed]
  15. Detection of coronary artery stenosis in children with Kawasaki disease. Usefulness of pharmacologic stress 201Tl myocardial tomography. Kondo, C., Hiroe, M., Nakanishi, T., Takao, A. Circulation (1989) [Pubmed]
  16. Quantitative adenosine 201Tl single-photon emission computed tomography for the early assessment of patients surviving acute myocardial infarction. Mahmarian, J.J., Pratt, C.M., Nishimura, S., Abreu, A., Verani, M.S. Circulation (1993) [Pubmed]
  17. Single-photon emission computed tomography gallium imaging versus computed tomography: predictive value in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation for non-Hodgkin's lymphoma. Vose, J.M., Bierman, P.J., Anderson, J.R., Harrison, K.A., Dalrymple, G.V., Byar, K., Kessinger, A., Armitage, J.O. J. Clin. Oncol. (1996) [Pubmed]
  18. Single-photon emission computed tomography quantitation of gallium citrate uptake for the differentiation of lymphoma from benign hilar uptake. Even-Sapir, E., Bar-Shalom, R., Israel, O., Frenkel, A., Iosilevsky, G., Haim, N., Epelbaum, R., Gaitini, D., Kolodny, G.M., Front, D. J. Clin. Oncol. (1995) [Pubmed]
  19. Prognostic value of dobutamine stress technetium-99m-sestamibi single-photon emission computed tomography myocardial perfusion imaging: stratification of a high-risk population. Calnon, D.A., McGrath, P.D., Doss, A.L., Harrell, F.E., Watson, D.D., Beller, G.A. J. Am. Coll. Cardiol. (2001) [Pubmed]
  20. Preoperative selection of patients with severely impaired left ventricular function for coronary revascularization. Role of low-dose dobutamine echocardiography and exercise-redistribution-reinjection thallium SPECT. Vanoverschelde, J.L., Gerber, B.L., D'Hondt, A.M., De Kock, M., Dion, R., Wijns, W., Melin, J.A. Circulation (1995) [Pubmed]
  21. [18F]fluorodeoxyglucose single photon emission computed tomography: can it replace PET and thallium SPECT for the assessment of myocardial viability? Srinivasan, G., Kitsiou, A.N., Bacharach, S.L., Bartlett, M.L., Miller-Davis, C., Dilsizian, V. Circulation (1998) [Pubmed]
  22. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Tjuvajev, J.G., Finn, R., Watanabe, K., Joshi, R., Oku, T., Kennedy, J., Beattie, B., Koutcher, J., Larson, S., Blasberg, R.G. Cancer Res. (1996) [Pubmed]
  23. Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype. van Dyck, C.H., Malison, R.T., Staley, J.K., Jacobsen, L.K., Seibyl, J.P., Laruelle, M., Baldwin, R.M., Innis, R.B., Gelernter, J. The American journal of psychiatry. (2004) [Pubmed]
  24. Independent contribution of myocardial perfusion defects to exercise capacity and heart rate recovery for prediction of all-cause mortality in patients with known or suspected coronary heart disease. Diaz, L.A., Brunken, R.C., Blackstone, E.H., Snader, C.E., Lauer, M.S. J. Am. Coll. Cardiol. (2001) [Pubmed]
  25. Changes in regional cerebral blood flow after a cold hand test in systemic lupus erythematosus patients with Raynaud's syndrome. Ferraccioli, G., Di Poi, E., Di Gregorio, F., Giacomuzzi, F., Guerra, U. Lancet (1999) [Pubmed]
  26. Intermediate-term clinical outcome following transmyocardial laser revascularization in patients with refractory angina pectoris. Landolfo, C.K., Landolfo, K.P., Hughes, G.C., Coleman, E.R., Coleman, R.B., Lowe, J.E. Circulation (1999) [Pubmed]
  27. Measurement of infarct size and percentage myocardium infarcted in a dog preparation with single photon-emission computed tomography, thallium-201, and indium 111-monoclonal antimyosin Fab. Johnson, L.L., Lerrick, K.S., Coromilas, J., Seldin, D.W., Esser, P.D., Zimmerman, J.M., Keller, A.M., Alderson, P.O., Bigger, J.T., Cannon, P.J. Circulation (1987) [Pubmed]
  28. Comparison of ictal SPECT and interictal PET in the presurgical evaluation of temporal lobe epilepsy. Ho, S.S., Berkovic, S.F., Berlangieri, S.U., Newton, M.R., Egan, G.F., Tochon-Danguy, H.J., McKay, W.J. Ann. Neurol. (1995) [Pubmed]
  29. Ictal single-photon emission computed tomography demonstrates localized epileptogenesis in cortical dysplasia. Kuzniecky, R., Mountz, J.M., Wheatley, G., Morawetz, R. Ann. Neurol. (1993) [Pubmed]
  30. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London. Andreasen, N.C., Rezai, K., Alliger, R., Swayze, V.W., Flaum, M., Kirchner, P., Cohen, G., O'Leary, D.S. Arch. Gen. Psychiatry (1992) [Pubmed]
  31. Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"): preliminary findings. Reneman, L., Lavalaye, J., Schmand, B., de Wolff, F.A., van den Brink, W., den Heeten, G.J., Booij, J. Arch. Gen. Psychiatry (2001) [Pubmed]
  32. Brain blood flow changes in depressed patients treated with interpersonal psychotherapy or venlafaxine hydrochloride: preliminary findings. Martin, S.D., Martin, E., Rai, S.S., Richardson, M.A., Royall, R. Arch. Gen. Psychiatry (2001) [Pubmed]
  33. Detection of coronary artery disease with myocardial contrast echocardiography: comparison with 99mTc-sestamibi single-photon emission computed tomography. Kaul, S., Senior, R., Dittrich, H., Raval, U., Khattar, R., Lahiri, A. Circulation (1997) [Pubmed]
  34. The dopamine transporter and neuroimaging in attention deficit hyperactivity disorder. Krause, K.H., Dresel, S.H., Krause, J., la Fougere, C., Ackenheil, M. Neuroscience and biobehavioral reviews. (2003) [Pubmed]
  35. Characterization of a 67Ga/68Ga radiopharmaceutical for SPECT and PET of MDR1 P-glycoprotein transport activity in vivo: validation in multidrug-resistant tumors and at the blood-brain barrier. Sharma, V., Prior, J.L., Belinsky, M.G., Kruh, G.D., Piwnica-Worms, D. J. Nucl. Med. (2005) [Pubmed]
  36. Dopamine D2 receptor occupancy by olanzapine or risperidone in young patients with schizophrenia. Lavalaye, J., Linszen, D.H., Booij, J., Reneman, L., Gersons, B.P., van Royen, E.A. Psychiatry research. (1999) [Pubmed]
  37. Brain perfusion and dopaminergic genes in boys with attention-deficit/hyperactivity disorder. Szobot, C., Roman, T., Cunha, R., Acton, P., Hutz, M., Rohde, L.A. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2005) [Pubmed]
  38. 99mTc-HMPAO brain single photon emission computerized tomography in mitochondrial encephalomyopathies. Yen, T.C., Yeh, S.H. Zhonghua Yi Xue Za Zhi (Taipei) (1995) [Pubmed]
  39. Selection of the optimal nonexercise stress for the evaluation of ischemic regional myocardial dysfunction and malperfusion. Comparison of dobutamine and adenosine using echocardiography and 99mTc-MIBI single photon emission computed tomography. Marwick, T., Willemart, B., D'Hondt, A.M., Baudhuin, T., Wijns, W., Detry, J.M., Melin, J. Circulation (1993) [Pubmed]
  40. Comparison of 201Tl, 99mTc-tetrofosmin, and dobutamine magnetic resonance imaging for identifying hibernating myocardium. Gunning, M.G., Anagnostopoulos, C., Knight, C.J., Pepper, J., Burman, E.D., Davies, G., Fox, K.M., Pennell, D.J., Ell, P.J., Underwood, S.R. Circulation (1998) [Pubmed]
  41. Value of combined approach with thallium-201 single-photon emission computed tomography and Epstein-Barr virus DNA polymerase chain reaction in CSF for the diagnosis of AIDS-related primary CNS lymphoma. Antinori, A., De Rossi, G., Ammassari, A., Cingolani, A., Murri, R., Di Giuda, D., De Luca, A., Pierconti, F., Tartaglione, T., Scerrati, M., Larocca, L.M., Ortona, L. J. Clin. Oncol. (1999) [Pubmed]
  42. A new technique for quantitative imaging of cerebrovascular reserve capacity using a double injection method with N-isopropyl-p-[123I]iodoamphetamine. Mori, K., Maeda, M., Asegawa, S., Masuda, Y., Takeoka, K. Neuroimage (1996) [Pubmed]
  43. Pinhole SPECT imaging of dopamine transporters correlates with dopamine transporter immunohistochemical analysis in the MPTP mouse model of Parkinson's disease. Andringa, G., Drukarch, B., Bol, J.G., de Bruin, K., Sorman, K., Habraken, J.B., Booij, J. Neuroimage (2005) [Pubmed]
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