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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Acute disseminated encephalomyelitis treated with plasmapheresis.

Accepted modes of therapy in acute disseminated encephalomyelitis include intravenous methyl prednisolone, intravenous immunoglobulin or a combination of both. Effectiveness of plasmapheresis has been demonstrated by previous case reports. We report two patients with steroid non-responsive acute disseminated encephalomyelitis in which plasmapheresis resulted in complete clinical and radiological recovery, though the therapy was initiated in the fifth week of illness. A total of 45-50 ml/kg body weight of plasma was removed in six equal exchanges over a period of two weeks. This report highlights that plasmapheresis could be of use even in the early second month of illness.[1]


  1. Acute disseminated encephalomyelitis treated with plasmapheresis. RamachandranNair, R., Parameswaran, M., Girija, A.S. Singapore medical journal. (2005) [Pubmed]
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