The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Multiple effects of caffeine on simulated high-intensity team-sport performance.

INTRODUCTION: Caffeine enhances performance of single bouts of endurance exercise, but its effects on repeated bouts typical of those in high-intensity team sports are unclear. PURPOSE: To investigate effects of caffeine in a performance test simulating physical and skill demands of a rugby union game. METHODS: The study was a double-blind, randomized, crossover design in which nine competitive male rugby players ingested either caffeine (6 body mass) or placebo (dextrose) 70 min before performing a rugby test. Each test consisted of seven circuits in each of two 40-min halves with a 10-min half-time rest. Each circuit included stations for measurement of sprint time (two straight-line and three agility sprints), power generation in two consecutive drives, and accuracy for passing balls rapidly. Interstitial fluid was sampled transdermally by electrosonophoresis before ingestion of caffeine or placebo and then before testing, at half-time, and immediately after testing; samples were assayed chromatographically for caffeine and epinephrine concentrations. RESULTS: The effects of caffeine on mean performance (+/-90% confidence limits) over all 14 circuits were: sprint speeds, 0.5% (+/-1.7%) through 2.9% (+/-1.3%); first-drive power, 5.0% (+/-2.5%); second-drive power, -1.2% (+/-6.8%); and passing accuracy, 9.6% (+/-6.1%). The enhancements were mediated partly through a reduction of fatigue that developed throughout the test and partly by enhanced performance for some measures from the first circuit. Caffeine produced a 51% (+/-11%) increase in mean epinephrine concentration; correlations between individual changes in epinephrine concentration and changes in performance were mostly unclear, but there were some strong positive correlations with sprint speeds and a strong negative correlation with passing accuracy. CONCLUSION: Caffeine is likely to produce substantial enhancement of several aspects of high-intensity team-sport performance.[1]


  1. Multiple effects of caffeine on simulated high-intensity team-sport performance. Stuart, G.R., Hopkins, W.G., Cook, C., Cairns, S.P. Medicine and science in sports and exercise. (2005) [Pubmed]
WikiGenes - Universities