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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Hairy cell leukemia: A diagnosis by endoscopic ultrasound guided fine needle aspiration.

ABSTRACT : BACKGROUND : Endosonography (EUS) guided FNA is a relatively new imaging modality which is increasingly used for sampling deep-seated lymph nodes in the diagnosis and staging of various malignancies, both primary as well as metastatic. It is also useful for staging of non-Hodgkin's lymphoma as well as diagnosing recurrence. The diagnosis of leukemia on FNA samples from deep-seated lymphadenopathy poses an even greater challenge. Hairy cell leukemia (HCL) is an uncommon, but distinct, lympho-proliferative disorder of B cell origin. It usually affects the spleen and bone marrow and uncommonly involves lymph nodes. There are only a few cases reported where HCL was diagnosed on FNA specimens. CASE PRESENTATION : We report the first case of HCL accurately rendered on EUS-FNA samples. CONCLUSION : This report underscores the concept that the presence of a cytopathologist in the endoscopy suite plays an important role in providing accurate diagnoses of lymphoid lesions biopsied with EUS-FNA.[1]

References

  1. Hairy cell leukemia: A diagnosis by endoscopic ultrasound guided fine needle aspiration. Meara, R.S., Reddy, V., Arnoletti, J.P., Jhala, D., Varadarajulu, S., Jhala, N. CytoJournal [electronic resource]. (2006) [Pubmed]
 
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