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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The gene for retinal rod 33-kDa protein is on mouse chromosome 1, near Lamb2.

A water-soluble protein (called "33-kDa protein") that exhibits light-dependent phosphorylation has been shown to be a major protein of mammalian rod photoreceptors. Although the function of this protein is unknown, it has been implicated in the biochemical cascade mediating the rod visual response. Using a retinal cDNA from the rat and somatic cell hybrids, we have mapped the gene corresponding to this protein to mouse Chromosome 1 and, by analyzing the progeny of an intersubspecific backcross, have positioned it near Lamb2 (the beta 2 chain of laminin). We have designated the gene Rpr-1 (rod photoreceptor protein-1).[1]


  1. The gene for retinal rod 33-kDa protein is on mouse chromosome 1, near Lamb2. Danciger, M., Kozak, C.A., Abe, T., Shinohara, T., Farber, D.B. Cytogenet. Cell Genet. (1991) [Pubmed]
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