Gene Review:
Neurod1 - neurogenic differentiation 1
Mus musculus
Synonyms:
BETA2, BHF-1, Beta-cell E-box transcriptional activator 2, Beta2, NeuroD1, ...
O'Driscoll,
Gammell,
Clynes,
Suzuki,
Takeda,
Obara,
Suzuki,
Mizoguchi,
Nishiyama,
Takeda,
Obara,
Kaneto,
Nakatani,
Miyatsuka,
Matsuoka,
Matsuhisa,
Hori,
Yamasaki,
Olson,
Asakura,
Snider,
Hawkes,
Strand,
Stoeck,
Hallahan,
Pritchard,
Tapscott,
Chen,
Lin,
Hamm,
Bendelac,
Rivera,
Park,
Roark,
Blednov,
Walker,
Alva,
Creech,
Findlay,
Harris,
Drexler,
Roether,
Jurd,
Rudolph,
Antkowiak,
- Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification. Akagi, T., Inoue, T., Miyoshi, G., Bessho, Y., Takahashi, M., Lee, J.E., Guillemot, F., Kageyama, R. J. Biol. Chem. (2004)
- E1A functions as a coactivator of retinoic acid-dependent retinoic acid receptor-beta 2 promoter activation. Kruyt, F.A., Folkers, G.E., Walhout, A.J., van der Leede, B.J., van der Saag, P.T. Mol. Endocrinol. (1993)
- Alterations in protein kinase C isozymes alpha and beta 2 in activated Ha-ras containing papillomas in the absence of an increase in diacylglycerol. Mills, K.J., Bocckino, S.B., Burns, D.J., Loomis, C.R., Smart, R.C. Carcinogenesis (1992)
- Glycogen synthase kinase 3beta together with 14-3-3 protein regulates diabetic cardiomyopathy: effect of losartan and tempol. Gurusamy, N., Watanabe, K., Ma, M., Prakash, P., Hirabayashi, K., Zhang, S., Muslin, A.J., Kodama, M., Aizawa, Y. FEBS Lett. (2006)
- Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor. Harrist, A., Beech, R.D., King, S.L., Zanardi, A., Cleary, M.A., Caldarone, B.J., Eisch, A., Zoli, M., Picciotto, M.R. Synapse (2004)
- Executive and social behaviors under nicotinic receptor regulation. Granon, S., Faure, P., Changeux, J.P. Proc. Natl. Acad. Sci. U.S.A. (2003)
- GABAA receptor alpha 1 and beta 2 subunit null mutant mice: behavioral responses to ethanol. Blednov, Y.A., Walker, D., Alva, H., Creech, K., Findlay, G., Harris, R.A. J. Pharmacol. Exp. Ther. (2003)
- The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion. Shoaib, M., Gommans, J., Morley, A., Stolerman, I.P., Grailhe, R., Changeux, J.P. Neuropharmacology (2002)
- Opposing actions of etomidate on cortical theta oscillations are mediated by different gamma-aminobutyric acid type A receptor subtypes. Drexler, B., Roether, C.L., Jurd, R., Rudolph, U., Antkowiak, B. Anesthesiology (2005)
- Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. Léna, C., Popa, D., Grailhe, R., Escourrou, P., Changeux, J.P., Adrien, J. J. Neurosci. (2004)
- Mouse CD1-specific NK1 T cells: development, specificity, and function. Bendelac, A., Rivera, M.N., Park, S.H., Roark, J.H. Annu. Rev. Immunol. (1997)
- M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Herwald, H., Cramer, H., Mörgelin, M., Russell, W., Sollenberg, U., Norrby-Teglund, A., Flodgaard, H., Lindbom, L., Björck, L. Cell (2004)
- A thyroid hormone receptor that is required for the development of green cone photoreceptors. Ng, L., Hurley, J.B., Dierks, B., Srinivas, M., Saltó, C., Vennström, B., Reh, T.A., Forrest, D. Nat. Genet. (2001)
- The nicotinic receptor beta 2 subunit is mutant in nocturnal frontal lobe epilepsy. De Fusco, M., Becchetti, A., Patrignani, A., Annesi, G., Gambardella, A., Quattrone, A., Ballabio, A., Wanke, E., Casari, G. Nat. Genet. (2000)
- Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. Malecki, M.T., Jhala, U.S., Antonellis, A., Fields, L., Doria, A., Orban, T., Saad, M., Warram, J.H., Montminy, M., Krolewski, A.S. Nat. Genet. (1999)
- Role of oncogenes and tumor suppressor genes in multistage carcinogenesis. Yuspa, S.H., Długosz, A.A., Cheng, C.K., Denning, M.F., Tennenbaum, T., Glick, A.B., Weinberg, W.C. J. Invest. Dermatol. (1994)
- Effects of a beta 3-adrenoceptor agonist, BRL 26830A, on insulin and glucagon release in mice. Yoshida, T., Hiraoka, N., Kondo, M. Endocrinol. Jpn. (1991)
- beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. Cohen, G., Han, Z.Y., Grailhe, R., Gallego, J., Gaultier, C., Changeux, J.P., Lagercrantz, H. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Expression of the protein tyrosine phosphatase beta2 gene in mouse erythroleukemia cells induces terminal erythroid differentiation. Kume, T., Watanabe, T., Sanokawo, R., Chida, D., Nakamura, T., Oishi, M. J. Biol. Chem. (1996)
- Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary tumor cells. Wood, W.M., Ocran, K.W., Gordon, D.F., Ridgway, E.C. Mol. Endocrinol. (1991)
- The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity. Kolterud, A., Alenius, M., Carlsson, L., Bohm, S. Development (2004)
- Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Ito, T., Udaka, N., Yazawa, T., Okudela, K., Hayashi, H., Sudo, T., Guillemot, F., Kageyama, R., Kitamura, H. Development (2000)
- Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Huang, H.P., Liu, M., El-Hodiri, H.M., Chu, K., Jamrich, M., Tsai, M.J. Mol. Cell. Biol. (2000)
- Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Chu, K., Tsai, M.J. Diabetes (2005)
- Transactivation of the mouse sulfonylurea receptor I gene by BETA2/NeuroD. Kim, J.W., Seghers, V., Cho, J.H., Kang, Y., Kim, S., Ryu, Y., Baek, K., Aguilar-Bryan, L., Lee, Y.D., Bryan, J., Suh-Kim, H. Mol. Endocrinol. (2002)
- Laminar organization of the mouse dentate gyrus: insights from BETA2/Neuro D mutant mice. Del Turco, D., Gebhardt, C., Burbach, G.J., Pleasure, S.J., Lowenstein, D.H., Deller, T. J. Comp. Neurol. (2004)
- Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus. Schwab, M.H., Bartholomae, A., Heimrich, B., Feldmeyer, D., Druffel-Augustin, S., Goebbels, S., Naya, F.J., Zhao, S., Frotscher, M., Tsai, M.J., Nave, K.A. J. Neurosci. (2000)
- Glucose regulates insulin gene transcription by hyperacetylation of histone h4. Mosley, A.L., Ozcan, S. J. Biol. Chem. (2003)
- CD11/CD18-independent neutrophil adherence to laminin is mediated by the integrin VLA-6. Bohnsack, J.F. Blood (1992)
- The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration. Tohyama, Y., Katagiri, K., Pardi, R., Lu, C., Springer, T.A., Kinashi, T. Mol. Biol. Cell (2003)
- PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Kaneto, H., Nakatani, Y., Miyatsuka, T., Matsuoka, T.A., Matsuhisa, M., Hori, M., Yamasaki, Y. Diabetes (2005)
- Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance. Gekeler, V., Boer, R., Uberall, F., Ise, W., Schubert, C., Utz, I., Hofmann, J., Sanders, K.H., Schächtele, C., Klemm, K., Grunicke, H. Br. J. Cancer (1996)
- An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium. Piguet, P.F., Vesin, C., Ryser, J.E., Senaldi, G., Grau, G.E., Tacchini-Cottier, F. Infect. Immun. (1993)
- RACK1 binds to a signal transfer region of G betagamma and inhibits phospholipase C beta2 activation. Chen, S., Lin, F., Hamm, H.E. J. Biol. Chem. (2005)
- Long-range interactions in neuronal gene expression: evidence from gene targeting in the GABA(A) receptor beta2-alpha6-alpha1-gamma2 subunit gene cluster. Uusi-Oukari, M., Heikkilä, J., Sinkkonen, S.T., Mäkelä, R., Hauer, B., Homanics, G.E., Sieghart, W., Wisden, W., Korpi, E.R. Mol. Cell. Neurosci. (2000)
- Identification of a functional NF-kappa B binding site in the murine T cell receptor beta 2 locus. Jamieson, C., Mauxion, F., Sen, R. J. Exp. Med. (1989)
- TcR recognition of the MHC-peptide dimer: structural properties of a ternary complex. Vasmatzis, G., Cornette, J., Sezerman, U., DeLisi, C. J. Mol. Biol. (1996)
- Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins. Jacobs, R.L., Devlin, C., Tabas, I., Vance, D.E. J. Biol. Chem. (2004)
- NeuroD2 is necessary for development and survival of central nervous system neurons. Olson, J.M., Asakura, A., Snider, L., Hawkes, R., Strand, A., Stoeck, J., Hallahan, A., Pritchard, J., Tapscott, S.J. Dev. Biol. (2001)
- Inhibition of BETA2/NeuroD by Id2. Ghil, S.H., Jeon, Y.J., Suh-Kim, H. Exp. Mol. Med. (2002)
- Quantitative analysis of expression of NeuroD, GAP43 and receptor tyrosine kinase B in developing mouse olfactory neuroepithelium. Yasui, R., Hasegawa, M., Doi, K., Shimizu, K., Ohtuski, N., Ishida, H., Nibu, K. Acta oto-laryngologica. Supplementum. (2004)
- Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Schwitzgebel, V.M., Scheel, D.W., Conners, J.R., Kalamaras, J., Lee, J.E., Anderson, D.J., Sussel, L., Johnson, J.D., German, M.S. Development (2000)
- An attempt to generate neurons from an astrocyte progenitor cell line FBD-104. Horiuchi, M., Tomooka, Y. Neurosci. Res. (2005)
- Expression in murine teratocarcinoma F9 cells of transcription factors involved in pancreas development. O'Driscoll, L., Gammell, P., Clynes, M. Transplant. Proc. (2004)
- NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Kojima, H., Fujimiya, M., Matsumura, K., Younan, P., Imaeda, H., Maeda, M., Chan, L. Nat. Med. (2003)
- Molecular cloning and characterization of a cDNA encoding a novel basic helix-loop-helix protein structurally related to Neuro-D/BHF1. Yasunami, M., Suzuki, K., Maruyama, H., Kawakami, H., Nagai, Y., Hagiwara, M., Ohkubo, H. Biochem. Biophys. Res. Commun. (1996)
- Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Naya, F.J., Huang, H.P., Qiu, Y., Mutoh, H., DeMayo, F.J., Leiter, A.B., Tsai, M.J. Genes Dev. (1997)
- NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system. Breslin, M.B., Zhu, M., Lan, M.S. J. Biol. Chem. (2003)
- Expression of NeuroD in the mouse taste buds. Suzuki, Y., Takeda, M., Obara, N. Cell Tissue Res. (2002)
- Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patches. Suzuki, Y., Mizoguchi, I., Nishiyama, H., Takeda, M., Obara, N. Chem. Senses (2003)