- Allosteric activation of the protein kinase PDK1 with low molecular weight compounds. Engel, M., Hindie, V., Lopez-Garcia, L.A., Stroba, A., Schaeffer, F., Adrian, I., Imig, J., Idrissova, L., Nastainczyk, W., Zeuzem, S., Alzari, P.M., Hartmann, R.W., Piiper, A., Biondi, R.M. EMBO J. (2006)