Role of plant CBP/p300-like genes in the regulation of flowering time.
CREB-binding protein ( CBP) and its homolog p300 possess histone acetyltransferase activity and function as key transcriptional co-activators in the regulation of gene expression that controls differentiation and development in animals. However, the role of CBP/p300-like genes in plants has not yet been elucidated. Here, we show that Arabidopsis CBP/p300-like genes promote flowering by affecting the expression of a major floral repressor FLOWERING LOCUS C ( FLC). Although animal CBP and p300 generally function as co-activators, Arabidopsis CBP/p300-like proteins are required for the negative regulation of FLC. This CBP/p300- mediated FLC repression may involve reversible protein acetylation independent of histone modification within FLC chromatin.[1]References
- Role of plant CBP/p300-like genes in the regulation of flowering time. Han, S.K., Song, J.D., Noh, Y.S., Noh, B. Plant J. (2007) [Pubmed]
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