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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The pattern of colorectal dysfunction changes with time since spinal cord injury.

BACKGROUND: Cross-sectional studies suggest that colorectal dysfunction after spinal cord injuries (SCI) worsens as time goes by. However, follow-up studies are needed to prove this. STUDY DESIGN: Prospective study. OBJECTIVE: To describe long-term colorectal function in SCI patients. SETTING: Members of the Danish Spinal Cord Injuries Association. METHODS: In 1996, 424 members of the Danish Paraplegic Association answered a detailed questionnaire describing their colorectal function. In 2006, those who continued as members (n=284) received an identical questionnaire. Data for patients responding both in 1996 and in 2006 (n=159) were compared. RESULTS: In 1996, 25% of the respondents reported that colorectal dysfunction had some or a major impact on their quality of life. At follow-up 10 years later, it was 38% (P<0.005). In 1996 11% defecated less than every second day and 16% spent more than 30 min at each defecation; in 2006, it was 19% (P<0.01) and 25% (P<0.00001), respectively. Digital anorectal stimulation or evacuation was performed at least once every week by 48% in 1996 and by 56% in 2006 (P<0.0001). Fecal incontinence was reported at least once a month by 22% in 1996 and by 17% in 2006 (P<0.001). CONCLUSION: While the frequency and severity of constipation-related symptoms increase with time since SCI, there is a decrease in the frequency of fecal incontinence.[1]

References

  1. The pattern of colorectal dysfunction changes with time since spinal cord injury. Faaborg, P.M., Christensen, P., Finnerup, N., Laurberg, S., Krogh, K. Spinal. Cord (2008) [Pubmed]
 
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