Disease relevance of Fecal Incontinence

• The causes of diarrhea in 11 patients consenting to this study were microscopic colitis, steatorrhea secondary to exocrine pancreatic insufficiency, dietary lactose or fructose malabsorption, anal sphincter dysfunction causing fecal incontinence, and the irritable bowel syndrome [1].
• METHODS: Nineteen patients (5 with spinal cord lesion, 6 with idiopathic fecal incontinence, and 8 with idiopathic constipation) treated with retrograde colonic washout took indium-111-labeled polystyrene pellets to label the bowel contents [2].
• PURPOSE: The aim of this trial was to compare lateral internal sphincterotomy with local 0.2 percent isosorbide dinitrate in the treatment of chronic anal fissure to minimize surgical complications such as minor fecal incontinence [3].
• After 2 weeks of orlistat treatment, the patient presented to the clinic with complaints of soft, fatty/oily stools, flatus with discharge, abdominal pain, increased flatus, and fecal incontinence [4].
• We report two children, suffering from idiopathic partial epilepsy, who started to present, in the same period of time, with epileptic negative myoclonus (ENM) in one lower limb and fecal incontinence (FI) [5].

High impact information on Fecal Incontinence

• Acute effect of diphenoxylate with atropine (Lomotil) in patients with chronic diarrhea and fecal incontinence [6].
• Fifteen patients with chronic diarrhea and fecal incontinence were admitted to a clinical research center and treated for 3 days with either placebo or diphenoxylate with atropine (Lomotil) [6].
• CONCLUSION: In patients with fecal incontinence and scleroderma, endoanal MR imaging helps delineate the anterior sphincter deformity and shows the slower gadolinium-enhancement pattern on dynamic studies of the internal sphincter [7].
• CONCLUSIONS: Simple anal sphincter electromyography can predict the outcome of the peripheral nerve evaluation with good positive predictive value and specificity in patients with fecal incontinence [8].
• BACKGROUND: Severe fecal incontinence remains a disabling condition for the patient and a major therapeutic challenge for the physician [9].

Chemical compound and disease context of Fecal Incontinence

• These results suggest that temporary or intermittent therapy with Lomotil and related drugs might benefit patients with chronic diarrhea and fecal incontinence [6].
• CONCLUSIONS: 1) Diarrhea is the most common aggravating factor for fecal incontinence, and antidiarrheal medications such as loperamide and diphenoxylate or bile acid binders may help [10].
• Randomized, controlled trial of topical phenylephrine for fecal incontinence in patients after ileoanal pouch construction [11].
• Therapy with an anal pacemaker and the beta 1 agonist, prenalterol, cured both bladder and fecal incontinence [12].
• RESULTS: Twenty-six patients were treated by wide local excision with microscopic clearance of resection margins, 15 by local excision with only macroscopic clearance of resection margins, 5 by CO2 laser vaporization, and 1 by abdominoperineal resection because of fecal incontinence [13].

Anatomical context of Fecal Incontinence

• Demonstration of the feasibility of implantation of a skeletal muscle pulse generator for fecal incontinence in a patient with an implanted unipolar DDD pacemaker [14].
• BACKGROUND: Gastrointestinal tract symptoms are common in patients with multiple sclerosis (MS), especially constipation and/or fecal incontinence [15].
• Two children with intractable fecal incontinence after correction of high anorectal malformations were successfully managed by the daily administration of a glycerin enema into the cecum via an appendicocecostomy or tubularized cecostomy, according to the method of Malone's antegrade continence enema (ACE) [16].

Gene context of Fecal Incontinence

• Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence [17].
• CONCLUSION: Urinary incontinence frequently coexists with fecal incontinence [18].
• Indications were as follows: APR + synchronous restoration of the excised sphincter by graciloplasty (n = 12); total anorectal reconstruction (TAR) following APR in the past (n = 6); Patients with acquired fecal incontinence (n = 4); and Congenital atresia (n = 6) [19].
• One-way ANOVA was used to correlate Fecal Incontinence Severity Index with quality-of-life measures [20].
• METHODS: We reviewed the records of all 22 patients with fecal incontinence secondary to obstetric trauma who were evaluated by endoanal ultrasound and underwent surgical management in our department from April to 1997 to April 2002 [21].

Analytical, diagnostic and therapeutic context of Fecal Incontinence

• The fecal incontinence group had a greater intake of carbohydrates, manganese, and vitamin B(1) compared with the control group [22].
• Routine midline episiotomy increases the risk of third- and fourth-degree perineal lacerations, which may lead to fecal incontinence [23].

References