Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Sofi, F. et al.

Francesco Sofi, Andrea Capalbo, Nicola Pucci, Jacopo Giuliattini, Francesca Condino, Flavio Alessandri, Rosanna Abbate, Gian Franco Gensini, Sergio Califano,

Cardiovascular evaluation, including resting and exercise electrocardiography, before participation in competitive sports: cross sectional study.

OBJECTIVE: To evaluate the clinical usefulness of complete preparticipation cardiovascular screening in a large cohort of sports participants. DESIGN: Cross sectional study of data over a five year period. SETTING: Institute of Sports Medicine in Florence, Italy. PARTICIPANTS: 30,065 (23,570 men) people seeking to obtain clinical eligibility for competitive sports. MAIN OUTCOME MEASURES: Results of resting and exercise 12 lead electrocardiography. RESULTS: Resting 12 lead ECG patterns showed abnormalities in 1812 (6%) participants, with the most common abnormalities (>80%) concerning innocent ECG changes. Exercise ECG showed an abnormal pattern in 1459 (4.9%) participants. Exercise ECG showed cardiac anomalies in 1227 athletes with normal findings on resting ECG. At the end of screening, 196 (0.6%) participants were considered ineligible for competitive sports. Among the 159 participants who were disqualified at the end of the screening for cardiac reasons, a consistent proportion (n=126, 79.2%) had shown innocent or negative findings on resting 12 lead ECG but clear pathological alterations during the exercise test. After adjustment for possible confounders, logistic regression analysis showed that age >30 years was significantly associated with an increased risk of being disqualified for cardiac findings during exercise testing. CONCLUSIONS: Among people seeking to take part in competitive sports, exercise ECG can identify those with cardiac abnormalities. Follow-up studies would show if disqualification of such people would reduce the incidence of CV events among athletes.[1]

References

Cardiovascular evaluation, including resting and exercise electrocardiography, before participation in competitive sports: cross sectional study. Sofi, F., Capalbo, A., Pucci, N., Giuliattini, J., Condino, F., Alessandri, F., Abbate, R., Gensini, G.F., Califano, S. BMJ (2008) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.