Early ventral expression of the Drosophila neurogenic locus mastermind.
The neurogenic locus mastermind ( mam) of Drosophila is required for the segregation of epidermal from neural cell lineages. Previous studies have shown that during neurogenesis mam appears to be expressed throughout the ectoderm, mesoderm, and neuroblast layer of the germ band. Here it is demonstrated that during early embryogenesis mam is expressed ubiquitously; however, the predominant domains of accumulation of mam RNA and protein during gastrulation are along the ventral longitudinal surface, including cells of the mesoderm, endoderm, mesectoderm, and neuroectoderm. The regions of elevated mam accumulation coincide with the realm of action of dorsoventral patterning genes.[1]References
- Early ventral expression of the Drosophila neurogenic locus mastermind. Bettler, D., Schmid, A., Yedvobnick, B. Dev. Biol. (1991) [Pubmed]
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