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Diabetic ketoacidosis, thyroiditis and alopecia areata in a child with Down syndrome.

A 10-year-old girl with Down syndrome and alopecia areata was admitted with severe ketoacidosis. She had high blood glucose level: 615 mg/dL and her HbAlc level was 13.3 %. After the control of ketoacidosis and reduction of the plasma glucose level, we found low free T4 level and high TSH levels. Thyroid peroxidase antibodies titer was 1383 IU/mL and both gliadin and endomysial antibodies were negative. This was the first report of a child with Down syndrome showing type 1 diabetes combined with alopecia areata and autoimmune thyroid disease.[1]

References

  1. Diabetic ketoacidosis, thyroiditis and alopecia areata in a child with Down syndrome. Pirgon, O., Atabek, M.E., Sert, A. Indian. J. Pediatr (2009) [Pubmed]
 
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