Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gorlitzer, M. et al.

Michael Gorlitzer, Gabriel Weiss, Reinhard Moidl, Sandra Folkmann, Ferdinand Waldenberger, Martin Czerny, Martin Grabenwöger, Gabriel Weiss, Reinhard Moidl, Sandra Folkmann, Ferdinand Waldenberger, Martin Czerny, Martin Grabenwöger,

Repair of stent graft-induced retrograde type A aortic dissection using the E-vita open prosthesis.

OBJECTIVES: Stent graft-induced retrograde type A dissection is a life-threatening complication after endovascular treatment of acute aortic type B dissections. METHODS: From August 2005 to February 2011, retrograde aortic dissection occurred in 4 of 29 patients (13.8%) undergoing thoracic endovascular aortic repair (TEVAR) for acute complicated aortic type B dissection. Three patients underwent emergent surgical conversion immediately after TEVAR. The operative strategy was a combined surgical and endovascular approach (frozen elephant trunk technique) using a specially designed hybrid prosthesis (Jotec E-vita open). All operations were performed under moderate hypothermia (25-28°C) and selective bilateral antegrade cerebral perfusion. The mean duration of circulatory arrest was 56 ± 7 min. Operative data and the outcome of surgery were analysed retrospectively. Data were analysed retrospectively in the limited number of patients. RESULTS: All patients survived the surgical procedure. No stroke, paraplegia, renal failure or other major complications occurred. Postoperative CT scans revealed perigraft thrombus formation and stable aortic dimensions in all patients after 6 months. In one patient, the retrograde dissection remained primarily undetected and untreated. The patient died suddenly, with no clinical signs, within 7 days after stent graft implantation. Autopsy revealed cardiac tamponade due to retrograde type A aortic dissection. CONCLUSIONS: Retrograde aortic dissection type A is a serious complication of thoracic endovascular repair of acute aortic type B dissection. Despite the small number of patients investigated in this study, the frozen elephant trunk technique appears to be a feasible bail-out strategy for the treatment of these acute aortic events.[1]

References

Repair of stent graft-induced retrograde type A aortic dissection using the E-vita open prosthesis. Gorlitzer, M., Weiss, G., Moidl, R., Folkmann, S., Waldenberger, F., Czerny, M., Grabenwöger, M. Eur. J. Cardiothorac. Surg (2012) [Pubmed]

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