Disease relevance of Prostheses and Implants

• Various complications have been reported recently for the Angelchik antireflux prosthesis, a silicone-gel prosthesis used in the treatment of gastroesophageal reflux and associated hiatal hernia [1].
• Coumarin agents provide adequate protection against thromboembolism during pregnancy in patients with mechanical valve prostheses [2].
• This report describes a case of antibiotic-resistant Salmonella heidelberg prosthetic hip infection successfully treated with prosthesis removal and once-daily ceftriaxone [3].
• The Angelchik prosthesis in this series has been safe, simple, and reproducible, and can eliminate the symptoms and signs of gastroesophageal reflux [4].
• In this study, our aim was to assess the effect of endoscopic insertion of hydrogel expandable prostheses into the oesophageal submucosa on spatiotemporal characteristics of gastro-oesophageal reflux [5].

Psychiatry related information on Prostheses and Implants

• The present results indicate that daily alcohol consumption and tobacco use may have a negative influence on predictable long-term implant treatment outcomes, producing peri-implant bone loss and compromising restorative treatment with implant-supported prostheses [6].
• The tests utilised are, STAI-Y (STAI-S for state anxiety, STAI-T for trait anxiety), BDI for depression, SP-it for stress events, SDS for somatoform disorders, The tests were given to patients at the first examination (t(0)) and at the check-up (t(1)) 1 month after the definitive prosthesis was cemented [7].
• OBJECTIVE: To evaluate the complications and prosthesis survival associated with implantation of the Mentor Alpha-1 inflatable penile prosthesis (IPP) for the treatment of erectile dysfunction (ED) [8].

High impact information on Prostheses and Implants

• Use of an antireflux prosthesis (Angelchik prosthesis) in the surgical treatment of symptomatic gastroesophageal reflux has increased steadily during the past several years [9].
• Gallium citrate Ga 67 scans and aortic prostheses [10].
• Life-threatening peri-prosthetic incompetence developed with two successive nickel-containing mitral-valve prostheses in a patient allergic to nickel [11].
• Disappearance of pruitus was achieved in seven of seven patients, and in 10 of 12 disappearance of jaundice (bilirubin, before prosthesis, 18.4 +/- 4.5 mg/dl [mean +/- 1 SD], bilirubin 1 month after prosthesis, 1.8 +/- 0.6 mg/dl [mean +/- 1 SD], P less than 0.001) with improvement of general clinical status was achieved [12].
• The self-expanding prosthesis was braided from 0.005-in Nitinol wires in the shape of two flat buttons with a short connecting waist with a diameter corresponding to that of the defect to be closed [13].

Chemical compound and disease context of Prostheses and Implants

• The risk of cholangitis, which used to be a major problem with transpapillary introduced prostheses of smaller calibre, seems definitely diminished by using one with a large calibre [14].
• Lethal progression of heart block after prosthesis cementing with methylmethacrylate [15].
• Protamine sulfate and vancomycin are synergistic against Staphylococcus epidermidis prosthesis infection in vivo [16].
• Four nafcillin-treated prostheses, six silver-pefloxacin-coated grafts, and 11 control grafts were interposed in the infrarenal aorta of dogs and immediately challenged with an intravenous infusion of 1 X 10(7) Staphylococcus aureus [17].
• Continual loading and articulation cycles undergone by metallic (e.g., titanium) alloy arthroplasty prostheses lead to liberation of a large number of metallic debris particulates, which have long been implicated as a primary cause of periprosthetic osteolysis and postarthroplasty aseptic implant loosening [18].

Biological context of Prostheses and Implants

• Prostheses containing bound tPA show fibrinolytic activity as measured both by lysis of clots formed in vitro, and by hydrolysis of a synthetic polypeptide substrate [19].
• PURPOSE: To explore electrically induced phosphenes in blind patients with retinitis pigmentosa (RP) in comparison with healthy subjects and to develop a screening test for candidates for an optic nerve visual prosthesis implantation [20].
• Periprosthetic bone remodelling of two types of uncemented femoral implant with proximal hydroxyapatite coating: a 3-year follow-up study addressing the influence of prosthesis design and preoperative bone density on periprosthetic bone loss [21].
• Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells [22].
• BTG was not a useful measure of the platelet activation induced by an arterial prosthesis [23].

Anatomical context of Prostheses and Implants

• Hemodynamics alterations induced by isoproterenol and pacing after aortic valve replacement with the Björk-Shiley or St. Jude medical prosthesis [24].
• Failure of adjusted doses of subcutaneous heparin to prevent thromboembolic phenomena in pregnant patients with mechanical cardiac valve prostheses [2].
• METHODS: Between July 2001 and July 2003, 26 patients with mitral valve prostheses (MVP) underwent circumferential pulmonary vein ablation for AF [25].
• CONCLUSION: Neointimal thickening and inflammatory reaction significantly increased with covered compared with noncovered prostheses in the iliac arteries in sheep and were worst with heparin-coated Dacron-covered stent-grafts [26].
• A ring-shaped radiopaque prosthesis was inserted at the esophagogastric junction in 93 patients for treatment of symptomatic gastroesophageal reflux [27].

Associations of Prostheses and Implants with chemical compounds

• Luminal surface production of 6-keto-PGF1 alpha from seeded prostheses was similar to aortic production and significantly greater (p less than .05) than that of control prostheses [28].
• In vivo function of glutaraldehyde-fixed porcine heterografts used for mitral valve replacement was evaluated by cardiac catheterization in 14 of our first 33 patients who have undergone mitral valve replacement with this prosthesis [29].
• A radiopaque marker was placed on the center of the free margin of each cusp, and the prostheses were implanted in the tricuspid position of dogs [30].
• To determine whether these reactions resulted primarily from transanastomotic pannus ingrowth, prostheses (30 mm x 4 mm) were constructed of three 10-mm long segments with Dacron segments on both ends and a middle polyglactin 910 (PG910) segment [31].
• Serial measurements of platelet survival were performed to assess platelet interaction with prostheses in vivo, and platelet serotonin was monitored as an index of platelet release in vivo [28].

Gene context of Prostheses and Implants

• Thus, this study demonstrated that gelatinase A and its activator might contribute to the aseptic loosening of polyethylene prostheses [32].
• The membrane-type-matrix metalloproteinase/matrix metalloproteinase-2/tissue inhibitor of metalloproteinase-2 system in periprosthetic connective-tissue remodeling in loose total-hip prostheses [33].
• PMN adhesion was decreased significantly (p<0.001) after the incubation of resting EC or TNFalpha-activated EC-seeded prostheses with a blocking monoclonal antibody (LYP20) directed against the P-selectin [34].
• The IL-6 level was not significantly altered, but was higher in patients with TiAIV prostheses than in those with a CrCoMo implant and in patients with cemented prostheses [35].
• Also, we found a significant (P < 0.05) correlation between the concentration of IL-12 and the concentration of MMP-1 in the patients with prosthesis loosening [36].

Analytical, diagnostic and therapeutic context of Prostheses and Implants

• Fluconazole may be useful follow-up therapy after a course of amphotericin B combined with resection arthroplasty or when removal of the prosthesis cannot be accomplished [37].
• PTFE-covered stents (group III) exhibited less NIH (p < 0.001) and luminal reduction (p < 0.01) than bare stents (group II) at the middle portion of the stent-graft, but the PTFE cover had no effect on NIH and lumen reduction at the proximal or distal ends of the prosthesis [38].
• Twenty-four of the prostheses were studied with technetium-99m methylene diphosphonate bone scintigraphy and 19 with Tc-99m sulfur colloid marrow scintigraphy [39].
• These data demonstrate that surfactant-treated prostheses can bind tPA, and that these chemically modified devices can act as a slow-release drug delivery system with the potential for reducing prosthesis-induced thromboembolism [19].
• This modified technique allows the hydroxyapatite ocular implants to be drilled for the final motility peg at an earlier time than currently possible, thereby resulting in more rapid cosmetic rehabilitation and obviating the need for secondary modification or replacement of the prosthesis [40].

References