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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Interactions of selenium and fluoride on growth, glycolysis and survival of Streptococcus mutans GS-5.

The effects of low concentrations (1.0 mmol/l of selenite and seleno-dl-cystine were tested alone, or in combination with NaF, on growth, glycolysis, and survival of Streptococcus mutans GS-5. In batch culture, both selenium-containing compounds (1.0 mmol/l) inhibited the growth rate and final cell yield by 92% or greater; glycolysis, however, was not affected. The observed bactericidal action of selenite at 0.1 mmol/l was pH-dependent. Fluoride reduced the killing effect of SeO3 in the culture medium and in a lactate-acetate buffer system at pH 6.5, 5.0 and 4. 0. These data indicate that selenium-containing compounds exert an antibacterial action on cells of S. mutans in a manner which leaves glycolysis unaffected.[1]

References

  1. Interactions of selenium and fluoride on growth, glycolysis and survival of Streptococcus mutans GS-5. Eisenberg, A.D., Curzon, M.E., Izaguirre-Fernàndez, E.J. Caries Res. (1990) [Pubmed]
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