Perforated jejunal diverticulum in the use of mycophenolate mofetil.
CONTEXT: Jejunal diverticulosis is a rare disease. Common acute complications include diverticulitis, intestinal obstruction, bleeding and perforation. Gastrointestinal tract perorations have also been rarely observed in the use of mycophenolate mofetil. CASE REPORT: We report a 44-year-old man with end-stage renal disease post failed kidney transplant on low-dose mycophenolate mofetil who presented with acute onset of abdominal pain. He was successfully given the diagnosis of perforated jejunal diverticulum. The patient successfully underwent a segmental jejunal resection and anastomosis. He unfortunately developed a recurrent jejunal perforation a month later and again had the second segmental jejunal resection operation. Mycophenolate mofetil then was discontinued. CONCLUSION: The present case illustrates jejunal diverticulum perforation in the use of mycophenolate mofetil. Physicians should increase the awareness of this association of perforated jejunal diverticulum in patients using mycophenolate mofetil.[1]References
- Perforated jejunal diverticulum in the use of mycophenolate mofetil. Thongprayoon, C., Cheungpasitporn, W., Edmonds, P.J., Thamcharoen, N. N. Am. J. Med. Sci (2014) [Pubmed]
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