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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Myxothiazol: a reversible blocker of the cell cycle.

Myxothiazol, a potent inhibitor of the cytochrome bc1 oxidoreductase, was shown by the use of flow cytometry to block reversibly the late G1/S phase of the cell cycle of human lymphoblastic T-cell line Jurkat (clone 886) at concentrations of 0.5 microgram/ml. These observations are compared to those of other drugs, such as antimycin, which effect the respiratory chain, and with O2-deficiency.[1]

References

  1. Myxothiazol: a reversible blocker of the cell cycle. Conradt, P., Dittmar, K.E., Schliephacke, H., Trowitzsch-Kienast, W. J. Antibiot. (1989) [Pubmed]
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