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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Facial paralysis and occult parotid cancer. A characteristic syndrome.

Extratemporal involvement of the seventh cranial nerve is often secondary to a tumor of the parotid gland. We describe six patients who had facial paralysis associated with an occult malignant neoplasm of the parotid gland. Initial evaluations in these patients, including computed tomography and magnetic resonance imaging, provided no evidence of a parotid tumor. Four of the six patients had a progressive triad of ear pain, facial paralysis, and sensory loss in the second and third divisions of the trigeminal nerve. This pattern indicates a high probability of a malignant lesion of the parotid gland, even in the presence of normal findings on noninvasive studies.[1]


  1. Facial paralysis and occult parotid cancer. A characteristic syndrome. Broderick, J.P., Auger, R.G., DeSanto, L.W. Arch. Otolaryngol. Head Neck Surg. (1988) [Pubmed]
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