The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Facial Paralysis

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Facial Paralysis


High impact information on Facial Paralysis

  • As for the hoxb-1 mutations, the facial paralysis observed in mice homozygous for the hoxb-2 mutation results from a failure to form the somatic motor component of the VIIth (facial) nerve which controls the muscles of facial expression [6].
  • Recently, we have discovered that the gonadal steroid, testosterone propionate (TP), accelerates recovery from facial paralysis in the hamster by increasing the rate of regeneration of the fastest regrowing axons [7].
  • Our objective was to determine the diagnostic value of CSF examinations in the diagnosis of neuroborreliosis in children with peripheral facial palsy (PFP) [8].
  • One patient had a complete facial palsy and sensorineural deafness on the involved side after surgery, with recurrence of the spasm 6 months later [9].
  • However, after the discontinuation of acyclovir therapy, peripheral facial palsy occurred on the left side [10].

Chemical compound and disease context of Facial Paralysis


Biological context of Facial Paralysis


Anatomical context of Facial Paralysis


Gene context of Facial Paralysis

  • Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis [16].
  • OBJECTIVES: To investigate the effects of injection of botulinum toxin type A (BTX A) into the orbicularis oculi muscle and lacrimal gland in patients with aberrant regeneration after facial palsy (facial synkinesias and hyperlacrimation) [22].
  • We describe a 9-year-old girl with the diagnosis of MRS who had episodic swelling of the upper lip and complete peripheral facial palsy, associated with herpes and recurrent bacterial infections [23].
  • In total, 100 sera obtained from patients with acute peripheral facial palsy were tested and judged blindly by two investigators [24].
  • Facial palsy began on average 7.6 years after the onset of MS but in five patients (4.7%) was the first symptom of MS, preceding the next MS symptom by 0.5-3 years [25].

Analytical, diagnostic and therapeutic context of Facial Paralysis


  1. Use of misoprostol during pregnancy and Möbius' syndrome in infants. Pastuszak, A.L., Schüler, L., Speck-Martins, C.E., Coelho, K.E., Cordello, S.M., Vargas, F., Brunoni, D., Schwarz, I.V., Larrandaburu, M., Safattle, H., Meloni, V.F., Koren, G. N. Engl. J. Med. (1998) [Pubmed]
  2. Neurological complications of neurofibromatosis type 1 in adulthood. Créange, A., Zeller, J., Rostaing-Rigattieri, S., Brugières, P., Degos, J.D., Revuz, J., Wolkenstein, P. Brain (1999) [Pubmed]
  3. Nonhaemorrhagic thalamic infarction. Clinical, neuropsychological and electrophysiological findings in four anatomical groups defined by computerized tomography. Graff-Radford, N.R., Damasio, H., Yamada, T., Eslinger, P.J., Damasio, A.R. Brain (1985) [Pubmed]
  4. Clinical features and prognosis of Miller Fisher syndrome. Mori, M., Kuwabara, S., Fukutake, T., Yuki, N., Hattori, T. Neurology (2001) [Pubmed]
  5. Hepatocyte growth factor levels in cerebrospinal fluid: a comparison between acute bacterial and nonbacterial meningitis. Nayeri, F., Nilsson, I., Hagberg, L., Brudin, L., Roberg, M., Söderström, C., Forsberg, P. J. Infect. Dis. (2000) [Pubmed]
  6. Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Barrow, J.R., Capecchi, M.R. Development (1996) [Pubmed]
  7. Testosterone enhancement of the nerve cell body response to injury: evidence using in situ hybridization and ribosomal DNA probes. Kinderman, N.B., Jones, K.J. J. Neurosci. (1993) [Pubmed]
  8. Diagnostic value of cerebrospinal fluid examination in children with peripheral facial palsy and suspected Lyme borreliosis. Albisetti, M., Schaer, G., Good, M., Boltshauser, E., Nadal, D. Neurology (1997) [Pubmed]
  9. Microvascular decompression of the facial nerve for hemifacial spasm: clinical and electrophysiologic observations. Auger, R.G., Piepgras, D.G., Laws, E.R., Miller, R.H. Neurology (1981) [Pubmed]
  10. Atypical brainstem encephalitis caused by herpes simplex virus 2. Chu, K., Kang, D.W., Lee, J.J., Yoon, B.W. Arch. Neurol. (2002) [Pubmed]
  11. MR imaging of facial nerve enhancement in Bell palsy or after temporal bone surgery. Daniels, D.L., Czervionke, L.F., Millen, S.J., Haberkamp, T.J., Meyer, G.A., Hendrix, L.E., Mark, L.P., Williams, A.L., Haughton, V.M. Radiology. (1989) [Pubmed]
  12. Ramsay Hunt syndrome. Sweeney, C.J., Gilden, D.H. J. Neurol. Neurosurg. Psychiatr. (2001) [Pubmed]
  13. Repeated facial palsies after chlorocresol inhalation. Døssing, M., Wulff, C.H., Olsen, P.Z. J. Neurol. Neurosurg. Psychiatr. (1986) [Pubmed]
  14. Testosterone-induced acceleration of recovery from facial paralysis following crush axotomy of the facial nerve in male hamsters. Kujawa, K.A., Kinderman, N.B., Jones, K.J. Exp. Neurol. (1989) [Pubmed]
  15. Successful oral doxycycline treatment of Lyme disease-associated facial palsy and meningitis. Dotevall, L., Hagberg, L. Clin. Infect. Dis. (1999) [Pubmed]
  16. Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis. van der Zwaag, B., Burbach, J.P., Brunner, H.G., van Bokhoven, H., Padberg, G.W. Brain Res. Dev. Brain Res. (2005) [Pubmed]
  17. Bilateral facial paralysis following ethylene glycol ingestion. Mallya, K.B., Mendis, T., Guberman, A. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (1986) [Pubmed]
  18. Temporal bone cholesteatoma. Charachon, R. The American journal of otology. (1985) [Pubmed]
  19. Topical papaverine and facial nerve dysfunction in cerebellopontine angle surgery. Eisenman, D.J., Digoy, G.P., Victor, J.D., Selesnick, S.H. The American journal of otology. (1999) [Pubmed]
  20. Facial paralysis and occult parotid cancer. A characteristic syndrome. Broderick, J.P., Auger, R.G., DeSanto, L.W. Arch. Otolaryngol. Head Neck Surg. (1988) [Pubmed]
  21. Three new patients with congenital unilateral facial nerve palsy due to chromosome 22q11 deletion. Puñal, J.E., Siebert, M.F., Angueira, F.B., Lorenzo, A.V., Castro-Gago, M. J. Child Neurol. (2001) [Pubmed]
  22. Botulinum toxin treatment of synkinesia and hyperlacrimation after facial palsy. Boroojerdi, B., Ferbert, A., Schwarz, M., Herath, H., Noth, J. J. Neurol. Neurosurg. Psychiatr. (1998) [Pubmed]
  23. Melkersson-Rosenthal syndrome in childhood: a challenge in differential diagnosis and treatment. Ziem, P.E., Pfrommer, C., Goerdt, S., Orfanos, C.E., Blume-Peytavi, U. Br. J. Dermatol. (2000) [Pubmed]
  24. Rapid strip assay for detection of anti-herpes simplex virus antibodies: application to prediction of varicella-zoster virus reactivation in patients with acute peripheral facial palsy. Ohtani, F., Furuta, Y., Horal, P., Bergström, T. J. Med. Virol. (2000) [Pubmed]
  25. Facial palsy in multiple sclerosis. Fukazawa, T., Moriwaka, F., Hamada, K., Hamada, T., Tashiro, K. J. Neurol. (1997) [Pubmed]
  26. Transient facial palsy in sphenoidal electrode placement. Iriarte, J., Parra, J., Kanner, A.M. Epilepsia (1996) [Pubmed]
  27. Varicella-zoster virus reactivation is an important cause of acute peripheral facial paralysis in children. Furuta, Y., Ohtani, F., Aizawa, H., Fukuda, S., Kawabata, H., Bergström, T. Pediatr. Infect. Dis. J. (2005) [Pubmed]
  28. Change in gene expression in facial nerve nuclei and the effect of superoxide dismutase in a rat model of ischemic facial paralysis. Mohri, D., Satomi, F., Kondo, E., Fukuoka, T., Sakagami, M., Noguchi, K. Brain Res. (2001) [Pubmed]
  29. Autoantibodies to human manganese superoxide dismutase (MnSOD) in children with facial palsy due to neuroborreliosis. Eiffert, H., Karsten, A., Ritter, K., Ohlenbusch, A., Schlott, T., Laskawi, R., Christen, H.J. Neuropediatrics. (2005) [Pubmed]
WikiGenes - Universities