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MeSH Review

Facial Nerve

 
 
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Disease relevance of Facial Nerve

 

Psychiatry related information on Facial Nerve

 

High impact information on Facial Nerve

  • Upon facial nerve transection, damaged CD200-deficient neurons elicited an accelerated microglial response [7].
  • Labeled cells were also observed in the major subdivisions of the amygdaloid complex, the olfactory bulb, the trochlear nerve nucleus, the dorsal tegmental region, the facial nerve nucleus, the nucleus of the spinal tract of the trigeminal nerve, and the spinal cord dorsal horn [8].
  • Seven days after facial nerve transection, both AChE mRNA and enzyme activity levels were markedly reduced in untreated and vehicle-treated facial motoneurons, suggesting positive regulation of motoneuron AChE expression by muscle-derived factors [9].
  • To evaluate whether endogenous CNTF, released after nerve injury from the cytosol of Schwann cells, supports motoneuron survival, we transected the facial nerve in 4-week-old pmn mice [10].
  • There was no significant difference in facial nerve outcome between intravenous and oral acyclovir treatment [11].
 

Chemical compound and disease context of Facial Nerve

 

Biological context of Facial Nerve

 

Anatomical context of Facial Nerve

 

Associations of Facial Nerve with chemical compounds

  • We have previously demonstrated that systemic administration of testosterone increases the rate of axonal regeneration following facial nerve crush in adult male hamsters [27].
  • Nimodipine accelerates axonal sprouting after surgical repair of rat facial nerve [28].
  • We report a 24-year-old woman with recurrent facial and lip swelling, lingua plicata, and peripheral facial-nerve palsy who benefited from a short course of high-dose i.v. methylprednisolone [29].
  • Most tracts had significantly higher activities than the cholinergic facial nerve root, consistent with the possibility that a component of aspartate aminotransferase activity might serve as a marker for neurons using glutamate and/or aspartate as neurotransmitter [30].
  • For identifying normal anatomic structures such as the facial nerve and the main duct, the administration of gadopentetate dimeglumine was helpful [31].
 

Gene context of Facial Nerve

  • Facial nerve lesion dramatically increased the number of surviving motoneurons in pmn mice [10].
  • Here we examined the regulation and function of p75NTR during regeneration after peripheral transection of the facial nerve of adult mice [32].
  • GDNF may therefore be useful in improving facial nerve regeneration in the clinic [33].
  • To test this hypothesis, we investigated adult mice constitutively deficient in the expression of TNC, TNR or both, using the facial nerve injury paradigm [34].
  • Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair [34].
 

Analytical, diagnostic and therapeutic context of Facial Nerve

References

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  16. Cranial neuropathy associated with chlorinated solvents. Re: Facial nerve palsy after acute exposure to dichloromethane. Liss, G.M., House, R.A., Wills, M.C. Am. J. Ind. Med. (2006) [Pubmed]
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  18. Distribution of the galectin-1 mRNA in the rat nervous system: its transient upregulation in rat facial motor neurons after facial nerve axotomy. Akazawa, C., Nakamura, Y., Sango, K., Horie, H., Kohsaka, S. Neuroscience (2004) [Pubmed]
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  20. PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis. van der Zwaag, B., Hellemons, A.J., Leenders, W.P., Burbach, J.P., Brunner, H.G., Padberg, G.W., Van Bokhoven, H. Dev. Dyn. (2002) [Pubmed]
  21. Effect of facial nerve transection on acetylcholinesterase, choline acetyltransferase and [3H]quinuclidinyl benzilate binding in rat facial nuclei. Hoover, D.B., Hancock, J.C. Neuroscience (1985) [Pubmed]
  22. Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats. Miller, F.D., Tetzlaff, W., Bisby, M.A., Fawcett, J.W., Milner, R.J. J. Neurosci. (1989) [Pubmed]
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  25. Interleukin-6 (IL6) and cellular response to facial nerve injury: effects on lymphocyte recruitment, early microglial activation and axonal outgrowth in IL6-deficient mice. Galiano, M., Liu, Z.Q., Kalla, R., Bohatschek, M., Koppius, A., Gschwendtner, A., Xu, S., Werner, A., Kloss, C.U., Jones, L.L., Bluethmann, H., Raivich, G. Eur. J. Neurosci. (2001) [Pubmed]
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  28. Nimodipine accelerates axonal sprouting after surgical repair of rat facial nerve. Angelov, D.N., Neiss, W.F., Streppel, M., Andermahr, J., Mader, K., Stennert, E. J. Neurosci. (1996) [Pubmed]
  29. Melkersson-Rosenthal syndrome treated by methylprednisolone. Kesler, A., Vainstein, G., Gadoth, N. Neurology (1998) [Pubmed]
  30. Aspartate aminotransferase activity in fiber tracts of the rat brain. Godfrey, D.A., Bowers, M., Johnson, B.A., Ross, C.D. J. Neurochem. (1984) [Pubmed]
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  33. Glial cell line-derived neurotrophic factor released by synthetic guidance channels promotes facial nerve regeneration in the rat. Barras, F.M., Pasche, P., Bouche, N., Aebischer, P., Zurn, A.D. J. Neurosci. Res. (2002) [Pubmed]
  34. Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair. Guntinas-Lichius, O., Angelov, D.N., Morellini, F., Lenzen, M., Skouras, E., Schachner, M., Irintchev, A. Eur. J. Neurosci. (2005) [Pubmed]
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