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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The alpha-spectrin gene is on chromosome 1 in mouse and man.

By using alpha-spectrin cDNA clones of murine and human origin and somatic cell hybrids segregating either mouse or human chromosomes, the gene for alpha-spectrin has been mapped to chromosome 1 in both species. This assignment of the mouse alpha-spectrin gene to mouse chromosome 1 by DNA hybridization strengthens the previous identification of the alpha-spectrin locus in mouse with the sph locus, which previously was mapped by linkage analysis to mouse chromosome 1, distal to the Pep-3 locus. By in situ hybridization to human metaphase chromosomes, the human alpha-spectrin gene has been localized to 1q22-1q25; interestingly, the locus for a non-Rh-linked form of elliptocytosis has been provisionally mapped to band 1q2 by family linkage studies.[1]

References

  1. The alpha-spectrin gene is on chromosome 1 in mouse and man. Huebner, K., Palumbo, A.P., Isobe, M., Kozak, C.A., Monaco, S., Rovera, G., Croce, C.M., Curtis, P.J. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
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