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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Prediction of intracerebral hemorrhage survival.

The Pilot Stroke Data Bank obtained information on 94 patients with intracerebral hemorrhage. These data were used to identify factors predictive of 30-day outcome from among 85 demographic, historical, clinical, and laboratory variables generally available to clinicians on the day of admission. The 9 univariate factors statistically associated with outcome were Glasgow Coma Scale score, systolic blood pressure, pulse pressure, horizontal and vertical gaze palsies, severity of weakness, presence of brainstem-cerebellar deficits, interval stroke course, and parenchymal hemorrhage size. Beginning with these factors, a step-down variable selection procedure was used to derive a logistic regression model, containing only Glasgow Coma Scale score, pulse pressure, and hemorrhage size, that could be used to categorize correctly 92% of the patients as alive or dead at 30 days after onset.[1]


  1. Prediction of intracerebral hemorrhage survival. Tuhrim, S., Dambrosia, J.M., Price, T.R., Mohr, J.P., Wolf, P.A., Heyman, A., Kase, C.S. Ann. Neurol. (1988) [Pubmed]
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