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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Median cleft of the upper lip associated with lipomas of the central nervous system and cutaneous polyps.

An unusual combination of three rare developmental anomalies, ie, complete median cleft lip, cutaneous polyps, and midline lipomas of the central nervous system, was discovered in a male newborn. Inguinal hernia, cryptorchidism, and clinodactyly of the fifth fingers were other features. His mother was found to have clinodactyly, antimongoloid slant to her palpebral fissures, and computed tomography (CT) scan evidence of asymptomatic hydrocephaly. Family history and clinical investigations did not reveal any clues to etiology. This combination of findings may represent a new syndrome or another expression of frontonasal dysplasia.[1]

References

  1. Median cleft of the upper lip associated with lipomas of the central nervous system and cutaneous polyps. Pai, G.S., Levkoff, A.H., Leithiser, R.E. Am. J. Med. Genet. (1987) [Pubmed]
 
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