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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC).

The preimplantation-embryo-development (Ped) gene influences the rate of cleavage division of preimplantation mouse embryos. The location of the Ped gene in the mouse major histocompatibility complex (MHC), the H-2 complex, has been inferred from the analysis of cleavage rates of embryos from mouse strains congenic at the H-2 complex. In this paper, formal genetic linkage studies were undertaken to evaluate linkage of the Ped gene to the H-2 complex. Co-segregation of Ped gene phenotype and H-2 haplotype was found in back-cross embryos. These data support the hypothesis that the Ped gene is linked to the H-2 complex.[1]

References

  1. Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC). Warner, C.M., Gollnick, S.O., Goldbard, S.B. Biol. Reprod. (1987) [Pubmed]
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