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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.

In situ nick translation procedures have been applied to meiotic metaphase I divisions of the normal and XY, Sxr mouse. Unlike in man, where the pairing tips of the XY bivalent show a special sensitivity to DNAse I nicking, no such sensitivity can be detected for either of these types of mouse. Hypersensitivity in the D-band equivalent region of the X chromosome does, however, exist, this site being early replicating in somatic cells and housing the X inactivation centre ( Xce).[1]

References

  1. Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I. Separovic, E.R., Chandley, A.C. Chromosoma (1987) [Pubmed]
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