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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Avian coccidiosis: the administration of encapsulated oocysts.

Oocysts of fowl coccidia, suspended in a 12% aqueous solution of alginic acid, were dropped into 5% calcium chloride solution to form beads. Following ingestion by chicks, excystation of sporozoites was not affected. Oocyst viability was best when beads were air-dried to 33% of their original weight and stored in airtight containers at 4 degrees C. Infectivity was fully maintained for 8 weeks. Trickle infection, using beads administered orally to 2- or 3-week-old chickens, or mixed daily in food of chicks from 1-day-old, established a high level of immunity. This method of oocyst administration offers some practical advantages for the conduct of immunity and chemotherapy experiments.[1]

References

  1. Avian coccidiosis: the administration of encapsulated oocysts. Norton, C.C., Joyner, L.P. Parasitology (1986) [Pubmed]
 
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