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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Tandem and inverted repeats of arginine genes in Escherichia coli: structural and evolutionary considerations.

Duplications of arg genes produced in the Rec+ and in the recA genetic backgrounds are shown by heteroduplex analysis to be strictly tandem at the level of resolution of this technique. The formation of these particular rearrangements therefore does not require the inclusion of transposons or other sequences of an appreciable size in their final structure. Duplications of short segments (about 2,000 nucleotides) appear unexpectedly stable when compared with duplications of longer segments (about 10,000 nucleotides). One of the structures analyzed displays two inversely repeated argE genes rearranged into an artificial divergent operon. The bearing of this observation on the origin of bipolar operons, of "mirror-image" map symmetries and on the production of inverted repeats in general, is discussed.[1]

References

  1. Tandem and inverted repeats of arginine genes in Escherichia coli: structural and evolutionary considerations. Charlier, D., Crabeel, M., Cunin, R., Glansdorff, N. Mol. Gen. Genet. (1979) [Pubmed]
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