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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A retrospective evaluation of nifedipine therapy in Prinzmetal's angina.

A retrosepctive evaluation has been made of blood pressure, pulse rate, and number of anginal attacks per day in twenty-one patients diagnosed as Prinzmetal's Angina and treated with the investigational drug nifedipine. The effect of combining nifedipine with short- and long-acting nitrates or with propranolol was also evaluated. In consideration of the statisically significant reduction in the number of anginal attacks per day, p less than 0.001, together with the non-significant mean changes in blood pressure and pulse rate as well as the compatibility with the other drugs, it is concluded that nifedipine is a very useful drug, in a dose range of 30--120 mg per day, for the treatment of Prinzmetal's Angina. Recorded side-effects were of minimal severity and in no case caused nifedipine therapy to be discontinued.[1]


  1. A retrospective evaluation of nifedipine therapy in Prinzmetal's angina. Battye, R., Ordille, C.M. J. Int. Med. Res. (1979) [Pubmed]
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