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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Membrane response to 1-methyladenine requires the presence of the nucleus.

Meiosis is re-initiated in starfish oocytes by the action of the hormone 1-methyladenine (1-MA). It is thought that the primary trigger is localised at the plasma membrane, and early changes reported are the activation of a Na+ pump and variation in membrane potential and conductance. We report here that external application of 1-MA results in an irreversible switching of the starfish oocyte membrane from one stable electrical state to another. This induced change requires the presence of the germinal vesicle.[1]

References

  1. Membrane response to 1-methyladenine requires the presence of the nucleus. Dale, B., de Santis, A., Hoshi, M. Nature (1979) [Pubmed]
 
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