The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

Biotransformation in the monkey of cartazolate (SQ 65,396), a substituted pyrazolopyridine having anxiolytic activity.

1. The metabolism of cartazolate (SQ 65,396), an anxiolytic agent, was studied in four male rhesus monkeys after oral administration. 2. Seven metabolites were identified in the pooled urine of the four monkeys. These resulted from a combination of (1) hydrolysis of the 5-carboxylic acid ethyl ester; (2) N-de-ethylation of the pyrazole ring; (3) gamma-hydroxylation of the n-butylamino side-chain; (4) removal of the n-butyl group; and (5) conjugation with beta-glucuronic acid.[1]

References

  1. Biotransformation in the monkey of cartazolate (SQ 65,396), a substituted pyrazolopyridine having anxiolytic activity. Kripalani, K.J., Dreyfuss, J., Nemec, J., Cohen, A.I., Meeker, F., Egli, P. Xenobiotica (1981) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities