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Chemical Compound Review

CARTAZOLATE     ethyl 2-butylamino-7-ethyl-5,7,8...

Synonyms: Cartazolato, Cartazolatum, CHEMBL8184, SureCN123839, CHEBI:103142, ...
 
 
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High impact information on SQ 65396

 

Anatomical context of SQ 65396

  • SQ 20009 and SQ 65396, two new pyrazolopyridines with anxiolytic properties in animals, reversibly increased Na+-independent 3H-GABA binding to rat cerabral cortex membranes in vitro [1].
 

Analytical, diagnostic and therapeutic context of SQ 65396

References

  1. In vitro modulation by SQ 20009 and SQ 65396 of GABA receptor binding in rat CNS membranes. Placheta, P., Karobath, M. Eur. J. Pharmacol. (1980) [Pubmed]
  2. Biotransformation in the monkey of cartazolate (SQ 65,396), a substituted pyrazolopyridine having anxiolytic activity. Kripalani, K.J., Dreyfuss, J., Nemec, J., Cohen, A.I., Meeker, F., Egli, P. Xenobiotica (1981) [Pubmed]
 
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