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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Cryoglobulins in Schistosoma haematobium infection.

The sera of school children with Schistosoma haematobium infection were tested for the presence of cold-insoluble immune complexes "the cryoglobulins". Two different methods were used: the standard macro-technique and the micro-adaptation technique. On using the standard macro-technique, 40 (32.8%) out of 122 schistosomiasis patients and 6 (7.5%) out of 80 control children were positive for cryoglobulins. Using the micro-adaptation technique, the corresponding numbers were 47 (38.5%) and 8 (10%), respectively. A comprehensive medical examination was carried out before treatment. After treatment with metrifonate (Bilarcil) the quantity of cryoglobulins and the number of children with cryoglobulins were significantly reduced to 12 (9.8%) when using macro-technique, and to 15 (12.3%) with micro-adaptation technique, thus suggesting a possible relationship of cryoglobulinaemia with urinary schistosomiasis. There was a significant difference in the number of sera found positive by the two techniques (X2 = 0.875, P less than 0.1).[1]

References

  1. Cryoglobulins in Schistosoma haematobium infection. Adeiga, A.A., Ade-Serrano, M.A. Acta Trop. (1983) [Pubmed]
 
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