Gene Review:
PHGDH - phosphoglycerate dehydrogenase
Homo sapiens
Synonyms:
3-PGDH, 3PGDH, D-3-phosphoglycerate dehydrogenase, HEL-S-113, NLS, ...
- Nucleotide sequence and differential expression of the human 3-phosphoglycerate dehydrogenase gene. Cho, H.M., Jun, D.Y., Bae, M.A., Ahn, J.D., Kim, Y.H. Gene (2000)
- 3-phosphoglycerate dehydrogenase deficiency in a patient with West syndrome. Pineda, M., Vilaseca, M.A., Artuch, R., Santos, S., García González, M.M., Aracil, A., Van Schaftingen, E., Jaeken, J. Developmental medicine and child neurology. (2000)
- HTLV-III env gene products synthesized in E. coli are recognized by antibodies present in the sera of AIDS patients. Crowl, R., Ganguly, K., Gordon, M., Conroy, R., Schaber, M., Kramer, R., Shaw, G., Wong-Staal, F., Reddy, E.P. Cell (1985)
- Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Padgett, R.A., Mount, S.M., Steitz, J.A., Sharp, P.A. Cell (1983)
- Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Lewis, H.A., Musunuru, K., Jensen, K.B., Edo, C., Chen, H., Darnell, R.B., Burley, S.K. Cell (2000)
- High incidence of precipitins in sera of heroin addicts. Smith, W.R., Wells, I.D., Glauser, F.L., Novey, H.S. JAMA (1975)
- Binding specificity of antiidiotypic autoantibodies to anti-DNA antibodies in humans. Sasaki, T., Muryoi, T., Takai, O., Tamate, E., Saito, H., Yoshinaga, K. J. Clin. Invest. (1988)
- Detection of antibodies against proteins modified by hydroxyethyl free radicals in patients with alcoholic cirrhosis. Clot, P., Bellomo, G., Tabone, M., Aricò, S., Albano, E. Gastroenterology (1995)
- The 200- and 150-kDa neurofilament proteins react with IgG autoantibodies from patients with kuru, Creutzfeldt-Jakob disease, and other neurologic diseases. Toh, B.H., Gibbs, C.J., Gajdusek, D.C., Goudsmit, J., Dahl, D. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Spectrum of natural antibodies against five HTLV-III antigens in infected individuals: correlation of antibody prevalence with clinical status. Franchini, G., Robert-Guroff, M., Aldovini, A., Kan, N.C., Wong-Staal, F. Blood (1987)
- HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal. Szabo, A., Dalmau, J., Manley, G., Rosenfeld, M., Wong, E., Henson, J., Posner, J.B., Furneaux, H.M. Cell (1991)
- Free intermingling of mammalian beta-tubulin isotypes among functionally distinct microtubules. Lewis, S.A., Gu, W., Cowan, N.J. Cell (1987)
- Human anticentromere antibodies: distribution, characterization of antigens, and effect on microtubule organization. Cox, J.V., Schenk, E.A., Olmsted, J.B. Cell (1983)
- Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Linzer, D.I., Levine, A.J. Cell (1979)
- An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies. Evans, D.J., McKeating, J., Meredith, J.M., Burke, K.L., Katrak, K., John, A., Ferguson, M., Minor, P.D., Weiss, R.A., Almond, J.W. Nature (1989)
- Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Gu, Y., Kuida, K., Tsutsui, H., Ku, G., Hsiao, K., Fleming, M.A., Hayashi, N., Higashino, K., Okamura, H., Nakanishi, K., Kurimoto, M., Tanimoto, T., Flavell, R.A., Sato, V., Harding, M.W., Livingston, D.J., Su, M.S. Science (1997)
- Type-restricted neutralization of molecular clones of human immunodeficiency virus. Looney, D.J., Fisher, A.G., Putney, S.D., Rusche, J.R., Redfield, R.R., Burke, D.S., Gallo, R.C., Wong-Staal, F. Science (1988)
- Sera from patients with poststreptococcal glomerulonephritis contain antibodies to glomerular heparan sulfate proteoglycan. Fillit, H., Damle, S.P., Gregory, J.D., Volin, C., Poon-King, T., Zabriskie, J. J. Exp. Med. (1985)
- Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products. Huff, J.P., Roos, G., Peebles, C.L., Houghten, R., Sullivan, K.F., Tan, E.M. J. Exp. Med. (1990)
- V490M, a common mutation in 3-phosphoglycerate dehydrogenase deficiency, causes enzyme deficiency by decreasing the yield of mature enzyme. Pind, S., Slominski, E., Mauthe, J., Pearlman, K., Swoboda, K.J., Wilkins, J.A., Sauder, P., Natowicz, M.R. J. Biol. Chem. (2002)
- Assignment of human 3-phosphoglycerate dehydrogenase (PHGDH) to human chromosome band 1p12 by fluorescence in situ hybridization. Baek, J.Y., Jun, D.Y., Taub, D., Kim, Y.H. Cytogenet. Cell Genet. (2000)
- Glutamate reduces secretion of l-serine in astrocytes isolated from stroke-prone spontaneously hypertensive rats. Yamagata, K., Shoji, Y., Terashima, T., Yokogoshi, H. Neuroscience (2006)
- Molecular characterization of 3-phosphoglycerate dehydrogenase deficiency--a neurometabolic disorder associated with reduced L-serine biosynthesis. Klomp, L.W., de Koning, T.J., Malingré, H.E., van Beurden, E.A., Brink, M., Opdam, F.L., Duran, M., Jaeken, J., Pineda, M., Van Maldergem, L., Poll-The, B.T., van den Berg, I.E., Berger, R. Am. J. Hum. Genet. (2000)
- Precursor and effector phenotypes of activated human T lymphocytes. Fainboim, L., Navarrete, C., Festenstein, H. Nature (1980)
- Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cells. Udeinya, I.J., Miller, L.H., McGregor, I.A., Jensen, J.B. Nature (1983)
- Recognition of a polymorphic monocyte antigen in HLA. van Leeuwen, A., Termijtelen, A., Shaw, S., van Rood, J.J. Nature (1982)
- Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling. O'Connor, K.H., Banga, J.P., Darmanin, C., El-Kabbani, O., Mackay, I.R., Rowley, M.J. J. Autoimmun. (2006)
- Human myasthenic sera reduce acetylcholine sensitivity of human muscle cells in tissue culture. Bevan, S., Kullberg, R.W., Heinemann, S.F. Nature (1977)
- Thymic factor in human sera demonstrable by a cyclic AMP assay. Astaldi, A., Astaldi, G.C., Schellekens, P.T., Eijswoogel, V.P. Nature (1976)
- Naturally occurring anti-idiotypic antibodies in myasthenia gravis patients. Dwyer, D.S., Bradley, R.J., Urquhart, C.K., Kearney, J.F. Nature (1983)
- Substituted ammonium ions as allergenic determinants in drug allergy. Baldo, B.A., Fisher, M.M. Nature (1983)
- Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Herrington, D.A., Clyde, D.F., Losonsky, G., Cortesia, M., Murphy, J.R., Davis, J., Baqar, S., Felix, A.M., Heimer, E.P., Gillessen, D. Nature (1987)