The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effect of aztreonam on the growth of Pasteurella multocida in the lung.

Specific-pathogen-free ICR mice were infected aerogenically with Pasteurella multocida and, beginning 1 hour later, were treated with aztreonam (50 mg/kg of body weight). The number of viable bacilli in the lungs, liver, and spleen were determined at intervals for up to 36 hours. Aztreonam was bactericidal for growing bacilli in vitro and, when injected 1 and 5 hours after aerogenic exposure, provided greater than 80% protection after dosage at the level of 12.5 mg/kg. Below this dosage level, viable organisms persisted in the lungs and the spleen and many of the minimally treated mice eventually died of pasteurellosis. The survivors developed active immunity as a result of the continued sublethal infection. Aztreonam protects mice against an aerogenic infection with highly virulent P multocida and may be useful in the prevention and treatment of pasteurellosis in cattle.[1]


WikiGenes - Universities