Developmental biology of a neural cell adhesion molecule.
A membrane glycoprotein isolated from embryonic brain has been shown to be a ligand in the formation of cell-cell bonds. The molecule, called neural cell adhesion molecule (N-CAM), participates in several aspects of neural development, including the formation of plexiform layers, neurite fasciculation and nerve-muscle interactions. Experiments in vivo indicate that N-CAM-mediated adhesion is essential to the orderly assembly of the visual system.[1]References
- Developmental biology of a neural cell adhesion molecule. Rutishauser, U. Nature (1984) [Pubmed]
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