Gene Review:
NCAM1 - neural cell adhesion molecule 1
Homo sapiens
Synonyms:
CD56, MSK39, N-CAM-1, NCAM, NCAM-1, ...
Puricelli,
Campa,
Enomoto,
Berezin,
Klementiev,
Ogata,
Esin,
Wagner,
Varela,
Colome-Grimmer,
Yarema,
Bouchard,
Satoh,
Secher,
Nabeshima,
Amano,
Suzuki,
Lastiri,
Nakayama,
Rh??aume,
Chalazonitis,
Faure,
Kos,
Murai,
Kowata,
Ishida,
Bal de Kier Joffé,
Novitskaia,
Favilli,
Numaoka,
Florio,
Kurokawa,
Glenthøj,
Maeda,
Nishida,
Chin,
Akiyama,
Bottai,
Aoki,
Sugawara,
Uchiyama,
Sampathkumar,
Gershon,
Chen-Tsai,
Gioseffi,
Batoni,
Oyake,
Ito,
Maisetta,
Guadalupe Pallotta,
Bock,
Pardini,
Setoyama,
Todaro,
Sacerdote de Lustig,
- Identification and characterization of TPARM gene in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2003)
- Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer. Tanaka, F., Otake, Y., Nakagawa, T., Kawano, Y., Miyahara, R., Li, M., Yanagihara, K., Nakayama, J., Fujimoto, I., Ikenaka, K., Wada, H. Cancer Res. (2000)
- Retinoic acid-induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells. Seidenfaden, R., Hildebrandt, H. J. Neurobiol. (2001)
- CD56: a useful marker for diagnosing Merkel cell carcinoma. Kurokawa, M., Nabeshima, K., Akiyama, Y., Maeda, S., Nishida, T., Nakayama, F., Amano, M., Ogata, K., Setoyama, M. J. Dermatol. Sci. (2003)
- Correlations among neural cell adhesion molecule, nerve growth factor, and its receptors, TrkA, TrkB, TrkC, and p75, in perineural invasion by basal cell and cutaneous squamous cell carcinomas. Chen-Tsai, C.P., Colome-Grimmer, M., Wagner, R.F. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. (2004)
- Association of neural cell adhesion molecule 1 gene polymorphisms with bipolar affective disorder in Japanese individuals. Arai, M., Itokawa, M., Yamada, K., Toyota, T., Arai, M., Haga, S., Ujike, H., Sora, I., Ikeda, K., Yoshikawa, T. Biol. Psychiatry (2004)
- Neural cell adhesion molecule in human serum. Increased levels in dementia of the Alzheimer type. Todaro, L., Puricelli, L., Gioseffi, H., Guadalupe Pallotta, M., Lastiri, J., Bal de Kier Joffé, E., Varela, M., Sacerdote de Lustig, E. Neurobiol. Dis. (2004)
- Aberrant splicing of neural cell adhesion molecule L1 mRNA in a family with X-linked hydrocephalus. Rosenthal, A., Jouet, M., Kenwrick, S. Nat. Genet. (1992)
- Reduced reactivity to novelty, impaired social behavior, and enhanced basal synaptic excitatory activity in perforant path projections to the dentate gyrus in young adult mice deficient in the neural cell adhesion molecule CHL1. Morellini, F., Lepsveridze, E., Kähler, B., Dityatev, A., Schachner, M. Mol. Cell. Neurosci. (2007)
- Cell-adhesion molecules, glucocorticoids and long-term-memory formation. Rose, S.P. Trends Neurosci. (1995)
- The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion. Freigang, J., Proba, K., Leder, L., Diederichs, K., Sonderegger, P., Welte, W. Cell (2000)
- X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Jouet, M., Rosenthal, A., Armstrong, G., MacFarlane, J., Stevenson, R., Paterson, J., Metzenberg, A., Ionasescu, V., Temple, K., Kenwrick, S. Nat. Genet. (1994)
- Alternative splicing generates a secreted form of N-CAM in muscle and brain. Gower, H.J., Barton, C.H., Elsom, V.L., Thompson, J., Moore, S.E., Dickson, G., Walsh, F.S. Cell (1988)
- Neuroprotection mediated by subtoxic dose of NMDA in SH-SY5Y neuroblastoma cultures: activity-dependent regulation of PSA-NCAM expression. Singh, J., Kaur, G. Brain Res. Mol. Brain Res. (2005)
- Human CD56bright and CD56dim natural killer cell subsets respond differentially to direct stimulation with Mycobacterium bovis bacillus Calmette-Guérin. Batoni, G., Esin, S., Favilli, F., Pardini, M., Bottai, D., Maisetta, G., Florio, W., Campa, M. Scand. J. Immunol. (2005)
- The expression pattern of CD56 (N-CAM) in human bone marrow biopsies infiltrated by acute leukemia. Khanlari, B., Buser, A., Lugli, A., Tichelli, A., Dirnhofer, S. Leuk. Lymphoma (2003)
- CD56-positive cells with or without synaptophysin expression are recognized in the pancreatic duct epithelium: a study with adult and fetal tissues and specimens from chronic pancreatitis. Fujisawa, M., Notohara, K., Tsukayama, C., Mizuno, R., Okada, S. Acta Med. Okayama (2003)
- Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain. Nakayama, J., Fukuda, M.N., Fredette, B., Ranscht, B., Fukuda, M. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Evidence for the presence of N-CAM 180 on astrocytes from rat cerebellum and differences in glycan structures between N-CAM 120 and N-CAM 140. Sasaki, T., Endo, T. Glia (1999)
- Gangliogenesis in the enteric nervous system: Roles of the polysialylation of the neural cell adhesion molecule and its regulation by bone morphogenetic protein-4. Faure, C., Chalazonitis, A., Rh??aume, C., Bouchard, G., Sampathkumar, S.G., Yarema, K.J., Gershon, M.D. Dev. Dyn. (2007)
- Costimulation of T cell receptor-triggered IL-2 production by Jurkat T cells via fibroblast growth factor receptor 1 upon its engagement by CD56. Kos, F.J., Chin, C.S. Immunol. Cell Biol. (2002)
- Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX. Angata, K., Suzuki, M., Fukuda, M. J. Biol. Chem. (1998)
- A Novel {alpha}-Helix in the First Fibronectin Type III Repeat of the Neural Cell Adhesion Molecule Is Critical for N-Glycan Polysialylation. Mendiratta, S.S., Sekulic, N., Hernandez-Guzman, F.G., Close, B.E., Lavie, A., Colley, K.J. J. Biol. Chem. (2006)
- Characterization of mouse ST8Sia II (STX) as a neural cell adhesion molecule-specific polysialic acid synthase. Requirement of core alpha1,6-linked fucose and a polypeptide chain for polysialylation. Kojima, N., Tachida, Y., Yoshida, Y., Tsuji, S. J. Biol. Chem. (1996)
- Molecular dissection of the ST8Sia IV polysialyltransferase. Distinct domains are required for neural cell adhesion molecule recognition and polysialylation. Angata, K., Chan, D., Thibault, J., Fukuda, M. J. Biol. Chem. (2004)
- Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM. Foley, D.A., Swartzentruber, K.G., Colley, K.J. J. Biol. Chem. (2009)
- ST8Sia II and ST8Sia IV polysialyltransferases exhibit marked differences in utilizing various acceptors containing oligosialic acid and short polysialic acid. The basis for cooperative polysialylation by two enzymes. Angata, K., Suzuki, M., Fukuda, M. J. Biol. Chem. (2002)
- Insights into GFRalpha1 regulation of neural cell adhesion molecule (NCAM) function from structure-function analysis of the NCAM/GFRalpha1 receptor complex. Sjöstrand, D., Ibáñez, C.F. J. Biol. Chem. (2008)
- Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway. Kolkova, K., Novitskaya, V., Pedersen, N., Berezin, V., Bock, E. J. Neurosci. (2000)
- Neurofilament and neural cell adhesion molecule immunocytochemistry of Huntington's disease striatum. Nihei, K., Kowall, N.W. Ann. Neurol. (1992)
- A neural cell adhesion molecule-derived fibroblast growth factor receptor agonist, the FGL-peptide, promotes early postnatal sensorimotor development and enhances social memory retention. Secher, T., Novitskaia, V., Berezin, V., Bock, E., Glenthøj, B., Klementiev, B. Neuroscience (2006)
- Clinical and biological significance of CD56 antigen expression in acute promyelocytic leukemia. Ito, S., Ishida, Y., Oyake, T., Satoh, M., Aoki, Y., Kowata, S., Uchiyama, T., Enomoto, S., Sugawara, T., Numaoka, H., Suzuki, K., Murai, K. Leuk. Lymphoma (2004)
- Expression cloning of a human sulfotransferase that directs the synthesis of the HNK-1 glycan on the neural cell adhesion molecule and glycolipids. Ong, E., Yeh, J.C., Ding, Y., Hindsgaul, O., Fukuda, M. J. Biol. Chem. (1998)
- Neural cell adhesion molecule (NCAM) induces neuronal phenotype acquisition in dominant negative MEK1-expressing hippocampal neural progenitor cells. Kim, B.W., Son, H. Exp. Mol. Med. (2006)
- Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III. Angata, K., Suzuki, M., McAuliffe, J., Ding, Y., Hindsgaul, O., Fukuda, M. J. Biol. Chem. (2000)
- Complementary DNA sequence encoding the major neural cell adhesion molecule isoform in a human small cell lung cancer cell line. Saito, S., Tanio, Y., Tachibana, I., Hayashi, S., Kishimoto, T., Kawase, I. Lung Cancer (1994)