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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Endocrine function following complex partial seizures.

Previous studies have demonstrated hyperprolactinemia following generalized tonic-clonic seizures and after electroconvulsive therapy. We found transient hyperprolactinemia following complex partial seizures but little change in serum gonadotropins, thyroid-stimulating hormone, growth hormone, or cortisol. Serum prolactin was invariably normal interictally. Postictal elevation of serum prolactin may represent a biochemical marker of complex partial seizures, and it offers a potential pathogenic mechanism for the sexual dysfunction that often complicates temporal lobe epilepsy.[1]


  1. Endocrine function following complex partial seizures. Pritchard, P.B., Wannamaker, B.B., Sagel, J., Nair, R., DeVillier, C. Ann. Neurol. (1983) [Pubmed]
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