Parallels in the epidemiology of selected anogenital carcinomas.
Characteristics of Los Angeles, Calif., residents in whom carcinomas of the cervix, vulva, vagina, anus, and penis were diagnosed during the period 1972-81 were compared with those of all residents and with those in whom any cancer was diagnosed during the same period. At all five sites, risks for squamous and transitional cell carcinomas generally increased with decreasing social class, were low among Jews (not explained by social class), and were elevated among persons who were separated or divorced at diagnosis compared to married persons. Single men had a striking excess of anal but not penile carcinomas. The five sites represent contiguous and histologically similar tissues, and the clinical literature suggests common risk factors, e.g., sexually transmitted infections and other forms of chronic irritation. These observations are all consistent with the hypothesis that tumors at these sites have common or similar etiologic elements.[1]References
- Parallels in the epidemiology of selected anogenital carcinomas. Peters, R.K., Mack, T.M., Bernstein, L. J. Natl. Cancer Inst. (1984) [Pubmed]
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