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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Effect of thyroxine-induced hyperthyroidism on some testicular enzymes of the pyruvate/malate cycle.

The effect of thyroxine on the specific activities of testicular enzymes of the pyruvate/malate cycle involved in lipogenesis were studied in prepubertal, pubertal and adult rats. Thyroxine (25 micrograms/100 g body weight) treatment for 1 month increased the specific activity of isocitrate dehydrogenase (NADP+) but the specific activities of ATP-citrate lyase, malate dehydrogenase and malic enzyme were inhibited. Withdrawal of thyroxine treatment from hyperthyroid rats brought back all enzyme activities to normal. The study reveals a direct, specific influence of thyroxine on different testicular enzymes of the pyruvate/malate cycle.[1]

References

  1. Effect of thyroxine-induced hyperthyroidism on some testicular enzymes of the pyruvate/malate cycle. Aruldhas, M.M., Valivullah, H.M., Govindarajulu, P. Biochim. Biophys. Acta (1984) [Pubmed]
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