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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Metaphase analysis of human lymphocytes treated with 4-chloromethylbiphenyl and benzyl chloride.

4CMB and BC caused mitotic inhibition in human lymphocytes at low doses (greater than 20 and greater than 10 microgram/ml respectively). At non-inhibitory concentrations, neither substance produced increases in cells with breaks or breaks per cell, although 4CMB did induce a significant increase in gaps at dose. 4CMB and BC are not chromosome mutagens in this system.[1]

References

  1. Metaphase analysis of human lymphocytes treated with 4-chloromethylbiphenyl and benzyl chloride. Kirkland, D.J., Smith, K.L., Jenkinson, P.C. Mutat. Res. (1982) [Pubmed]
 
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