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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Acute toxicity of propoxur on carbohydrate metabolism of Indian catfish (Heteropneustes fossilis).

Exposure of Indian catfish (Heteropneustes fossilis) to 5.20 ppm propoxur for 3, 6, 12, 48 and 96 h caused muscle glycogen depletion at 12 h and hepatic glycogenolysis at 3, 12, 48 and 96 h; hyperglycemia developed at all time-intervals. Blood pyruvate levels increased significantly at 12 and 48 h. Hyperlacticemia was observed at 6 h but hypolacticemia resulted at 12, 48 and 96 h in pesticide-treated fish. The observed effects are explained in terms of acute stress syndrome; possible mechanisms underlying the effect of anticholinesterase action of propoxur on carbohydrate metabolism are also discussed.[1]


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