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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro.

Rhodamine-123, a cationic laser dye, markedly reduced the clonal growth of carcinoma cells but had little effect on nontumorigenic epithelial cells in vitro. This selective inhibitory effect of Rhodamine-123 on some carcinomas is unusual since known anticancer drugs, such as arabinosyl cytosine and methotrexate, have not been shown to exhibit such selectivity in vitro.[1]

References

  1. Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro. Bernal, S.D., Lampidis, T.J., Summerhayes, I.C., Chen, L.B. Science (1982) [Pubmed]
 
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