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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sperm penetration into cervical mucus in vitro. II. Human spermatozoa in bovine mucus.

Human spermatozoa pentrate estrous bovine cervical mucus readily in vitro and maintain good motility and viability for a number of hours. They show pronounced unidirectional motion in mucus that has been aligned linearly. Data from tube preparations indicate that human spermatozoa from a given ejaculate travel more rapidly in estrous bovine mucus than in human midcyle mucus. They are prevented from penetrating luteal phase bovine mucus. The results are discussed in relation to a model of the molecular structure of cervical mucus, derived from laser light-scattering spectroscopy. In addition, it is suggested that bovine cervical mucus could be developed as a possible substitute for human cervical mucus in cases of infertility due to deficient endogenous mucus.[1]


  1. Sperm penetration into cervical mucus in vitro. II. Human spermatozoa in bovine mucus. Gaddum-Rosse, P., Blandau, R.J., Lee, W.I. Fertil. Steril. (1980) [Pubmed]
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