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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Identification and quantification of alpha-amino adipic acid in bovine dentine phosphoprotein.

A unique phosphoprotein, which contains an uncommon amino acid, alpha-amino adipic acid (alpha-AAA), was isolated from unerupted bovine teeth by extensive EDTA demineralization. The alpha-AAA in the protein hydrolysates was identified based on the elution time on an amino acid analyzer using the sodium and lithium citrate buffer in a dual column system, and its identity was confirmed by comparisons of its DNS derivative with that of authentic alpha-AAA. This result suggests that the lysine residues in the phosphoprotein may be deaminated by an amine oxidase into allysine and further oxidized to alpha-AAA.[1]

References

  1. Identification and quantification of alpha-amino adipic acid in bovine dentine phosphoprotein. Hiraoka, B.Y., Fukasawa, K., Fukasawa, K.M., Harada, M. J. Biochem. (1980) [Pubmed]
 
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