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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Fetal heart rate changes after accidental intrauterine lidocaine.

Fetal heart rate (FHR) decelerations resembling post-paracervical block (PCB) bradycardia were observed immediately after the inadvertent intrauterine injection of lidocaine hydrochloride. A review of the pathophysiology of post-PCB bradycardia is presented. The administration of a local anesthetic, either into the paracervical tissues or directly into the uterine cavity, may precipitate FHR decelerations principally, through arterial vasoconstriction with subsequent reflex responses and/or hypoxia in the fetus.[1]

References

  1. Fetal heart rate changes after accidental intrauterine lidocaine. Van Dorsten, J.P., Miller, F.C. Obstetrics and gynecology. (1981) [Pubmed]
 
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